【発明の名称】HIV感染およびエイズを対象としたリボザイム遺伝子治療 - The Regents of the University of California

Title:

【発明の名称】HIV感染およびエイズを対象としたリボザイム遺伝子治療

Document Type and Number:

Japanese Patent JPH08510134

Kind Code:

A

Abstract:

This invention provides an infectious retrovirus having inserted between the 5' and 3' long terminal repeat sequences of the retrovirus a nucleic acid encoding an anti-HIV-type specific agent or a foreign nucleic acid under the control of a pol III promoter. Host cells containing the retroviral vectors of this invention also are provided. Further provided are methods of interfering with or preventing HIV viral replication in a cell infected with HIV or likely to be infected with HIV.

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Inventors:

Wong-Staal, Flossie
Yu, Mang
Yamada, Osam
Ojiwang, Joe Sure.
Levit, Mark
Ho, Anthony

Application Number:

JP52582494A

Publication Date:

October 29, 1996

Filing Date:

May 17, 1994

Export Citation:

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Assignee:

The Regents of the University of California

International Classes:

C12N15/09; A61K31/70; A61K35/12; A61K35/14; A61K35/407; A61K35/44; A61K35/76; A61P31/12; A61P31/18; C07H21/04; C12N5/10; C12N9/00; C12N15/113; C12N15/867; A61K38/00; A61K48/00; C12R1/92; (IPC1-7): C12N15/09; A61K31/70; A61K35/12; A61K35/14; A61K35/407; A61K35/44; A61K35/76; C07H21/04; C12N5/10; C12N9/00

Attorney, Agent or Firm:

Atsushi Nakajima (4 people outside)

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