Title:
【発明の名称】脂環式ケトン、その製造方法および官能的性質および匂いの性質を付与、変調または改善する方法
Document Type and Number:
Japanese Patent JP2735600
Kind Code:
B2
Abstract:
Cycloaliphatic ketones of formula …… in which the wavy line denotes a C-C bond of cis or trans configuration, are prepared from an enolate of formula …… in which the wavy line has the meaning shown above and Me defines an alkali metal atom, preferably lithium, or magnesium, by treatment with a proton-donating chiral reactant consisting of a difunctional nitrogen-containing derivative of formula …… in which… - the asterisk defines a chirality centre;… - the subscript n has the value of zero or 1;… - each of the symbols R<0> and R<1> defines a linear or branched alkyl or aralkyl radical, or one of the two denotes a hydrogen atom and the other an alkyl radical as defined above;… - each of R<2> and R<3> defines a linear or branched alkyl radical, or one of the two denotes a hydrogen atom and the other an alkyl radical as defined above; and… - Z is used to define an OH group or a divalent radical HN-C(O), in which the nitrogen atom is bonded to the carbon atom in position 3 and the carbonyl group is bonded to the nitrogen atom in position 1;… - and in which the nitrogen atom in position 1 may be bonded to a benzyl group of a polystyrene resin;… hydrolysis of the reaction mixture and isomerisation by means of an isomerising agent according to the usual methods. …The cycloaliphatic ketones (I) are also obtained by a process starting with an organomagnesium derivative of formula …… in which the wavy line has the meaning shown above and X denotes a halogen atom, with at least one equivalent of a lithium alcoholate, via the presumed formation of a mixed 1:1 lithium-magnesium complex. …The ketones (1) are products which have advantageous organoleptic properties and as a result find a use as perfuming and flavouring ingredients.
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Inventors:
SHARURU FUEERU
JOSE GYARANDO
JOSE GYARANDO
Application Number:
JP2595989A
Publication Date:
April 02, 1998
Filing Date:
February 06, 1989
Export Citation:
Assignee:
FUIRUMENITSUHI SA
International Classes:
A23L2/00; A23L29/00; A24B15/28; A61K8/35; A61Q13/00; C07B31/00; C07B53/00; C07C45/00; C07C45/42; C07C45/67; C07C49/21; C07C49/557; C07C67/00; C07C403/00; C11B9/00; (IPC1-7): C07C49/21; A23L1/03; A23L2/00; A24B15/28; A61K7/46; C07C45/42; C07C45/67; C11B9/00
Attorney, Agent or Firm:
Toshio Yano