Title:
フルクトース-1,6-ビスホスファターゼ阻害薬としてのイミダゾール誘導体およびそれらを含む医薬組成物
Document Type and Number:
Japanese Patent JP5075124
Kind Code:
B2
Abstract:
Imidazole derivatives of formula (I):
wherein R 1 , R 2a , R 2b , A, V and W are as defined in the description,
as inhibitors of fructose-1,6-bisphosphatase,
their preparation process and
their use in the prevention or treatment of diabetes, and other diseases where the inhibition of gluconeogenesis, control of blood glucose levels, reduction in glycogen stores, or reduction in insulin levels is beneficial and diseases related to the insulin resistance syndrome.
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Inventors:
Carniat, Deni
Moine, Gerard
Boton, Gerard
Alberrod Vacu, Annik
Odi, Anik
Moine, Gerard
Boton, Gerard
Alberrod Vacu, Annik
Odi, Anik
Application Number:
JP2008524392A
Publication Date:
November 14, 2012
Filing Date:
July 19, 2006
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07D233/64; A61K31/4174; A61K31/4178; A61K31/4245; A61K31/4439; A61K31/4709; A61P3/06; A61P3/10; A61P9/10; A61P43/00; C07D401/12; C07D401/14; C07D409/04; C07D413/14
Domestic Patent References:
| JP6503335A | ||||
| JP3504728A |
Attorney, Agent or Firm:
Naotoshi Ikeda
Akio Miyazaki
Ishibashi Masayuki
Masaaki Ogata
Akio Miyazaki
Ishibashi Masayuki
Masaaki Ogata