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Title:
METHOD FOR SYNTHESIZING 2,4-DIMETHYLPYRIMIDINE-5-OL, NOVEL INTERMEDIATE FOR THE METHOD, AND USE OF PRODUCT IN SYNTHESIS OF LEMBOREXANT
Document Type and Number:
Japanese Patent JP2023017733
Kind Code:
A
Abstract:
To provide a novel method for synthesizing 2,4-dimethylpyrimidine-5-ol, a novel intermediate for the method, and use of a product in the synthesis of lemborexant.SOLUTION: The present invention provides a novel method for synthesizing 2,4-dimethylpyrimidine-5-ol, which is an important intermediate in synthesis of lemborexant, a novel intermediate for the method, and use of a product in the synthesis of lemborexant.SELECTED DRAWING: Figure 1

Inventors:
ABDESLAM AKHATOU
ALICIA DOBARRO RODRIGUEZ
Application Number:
JP2022117102A
Publication Date:
February 07, 2023
Filing Date:
July 22, 2022
Export Citation:
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Assignee:
MOEHS IBERICA SL
International Classes:
C07C221/00; A61K31/506; A61P25/20; C07C205/37; C07C225/14; C07D239/34; C07D239/36; C07D401/12
Attorney, Agent or Firm:
Nobutaka Yokota
Yasutaka Enoki
Michiko Omori
Akabane Momoko
Naokazu Uchiyama