Title:
NITROGEN-CONTAINING SPIRO RING COMPOUND AND ITS MEDICAL APPLICATION
Document Type and Number:
Japanese Patent JP2014141516
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a new compound useful for the treatment or prevention of immunological rejection or the like upon organ transplantation.SOLUTION: Provided is a new nitrogen-containing spiro ring compound including the following compound: the compound has a janus kinase 3(JAK3) antagonism and janus kinase 2(JAK2) antagonism, and is useful for the treatment or prevention of rejection upon organ transplantation or graft versus host disease reaction, autoimmune disease, allergic disease, chronic bone marrow proliferative disease, articular rheumatism, psoriasis or the like after the transplantation.
Inventors:
NOMICHI SATORU
SHIOZAKI MAKOTO
MIURA TOMOYA
HARA YOSHINORI
YAMANAKA HIROSHI
MAEDA KATSUYA
HORI AKIMI
INOUE AKIFUMI
HASE YASUNORI
SHIOZAKI MAKOTO
MIURA TOMOYA
HARA YOSHINORI
YAMANAKA HIROSHI
MAEDA KATSUYA
HORI AKIMI
INOUE AKIFUMI
HASE YASUNORI
Application Number:
JP2014077850A
Publication Date:
August 07, 2014
Filing Date:
April 04, 2014
Export Citation:
Assignee:
JAPAN TOBACCO INC
International Classes:
C07D519/00; A61K31/519; A61K31/52; A61K31/55; A61P7/00; A61P17/06; A61P29/00; A61P35/02; A61P37/06; A61P37/08; A61P43/00
Domestic Patent References:
| JP5520158B2 | 2014-06-11 |
Attorney, Agent or Firm:
Samejima Mutsumi
Kyousei Tamura
Masahiro Nitta
Kure Hidenori
Kyousei Tamura
Masahiro Nitta
Kure Hidenori
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