Title:
パクリタキセル溶媒化合物
Document Type and Number:
Japanese Patent JP4451660
Kind Code:
B2
Abstract:
Biologically active crystalline solvates of paclitaxel are precipitated using polar, aprotic, organic solvents. A pharmaceutical composition is also disclosed, as well as the preparation of the novel solvates and their uses as anti-tumor agents.
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Inventors:
Daniel A. Benini
Jack Z Googoustus
John Di Dimarco
Jack Z Googoustus
John Di Dimarco
Application Number:
JP2003548769A
Publication Date:
April 14, 2010
Filing Date:
November 25, 2002
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C07D305/14; A61K31/337; A61P35/00; C07C233/03; C07C233/05; C07C255/03; C07C317/04; C07D409/12
Domestic Patent References:
| JP11060565A | ||||
| JP11500753A | ||||
| JP10085502A | ||||
| JP1287056A | ||||
| JP7503460A | ||||
| JP64013070A |
Foreign References:
| WO2000078741A1 | ||||
| WO1999016759A1 |
Other References:
第4版 実験化学講座I 基本操作I,丸善株式会社,1990年,第184-186頁
化学実験操作法 上巻,株式会社南江堂,1963年,第377-379頁
新実験化学講座18 界面とコロイド,丸善株式会社,1977年,第348-349頁
化学実験操作法 上巻,株式会社南江堂,1963年,第377-379頁
新実験化学講座18 界面とコロイド,丸善株式会社,1977年,第348-349頁
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto
Shinichiro Yamanaka
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto
Shinichiro Yamanaka