PHENYLUREA DERIVATIVE

Title:

PHENYLUREA DERIVATIVE

Document Type and Number:

Japanese Patent JP2003192659

Kind Code:

A

Abstract:

To provide a drug containing a phenylnaphthylurea derivative or a salt thereof as an active ingredient.

This drug contains a compound of general formula (I) {e.g. N-(3,4-dichlorophenyl)-N'-[2-(2-hydroxyethyl)phenyl]urea} as the active ingredient. This drug exhibits high activity as a VRI antagonist and is useful for preventing and treating diseases associated with VRI activity, especially for treating impending incontinence, bladder hyperactivity, chronic pain, neuropathic pain, postoperative pain, chronic articular rheumatic pain, neuralgia, neuropathy, hyperesthesia dolorosa, nerve injury, ischemic diseases, neurodegeneration, apoplexy, incontinence and/or inflammatory diseases.

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Inventors:

YURA TAKESHI
MOGI MUNEHITO
IKEGAMI YUKA
MASUDA TSUTOMU
KOKUBO TOSHIO
URBAHNS KLAUS
YOSHIDA NAGAHIRO
MARUMO MAKIKO
SHIROO MASAHIRO
TAJIMI MASAOMI
TAKESHITA KEISUKE
MORIWAKI TOSHIYA
TSUKIMI YASUHIRO

Application Number:

JP2001395032A

Publication Date:

July 09, 2003

Filing Date:

December 26, 2001

Export Citation:

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Assignee:

BAYER AG

International Classes:

C07D295/12; A61K31/17; A61K31/245; A61K31/277; A61K31/341; A61K31/36; A61K31/381; A61K31/403; A61K31/416; A61K31/4406; A61K31/4409; A61K31/451; A61K31/47; A61P9/00; A61P9/10; A61P13/02; A61P13/10; A61P19/02; A61P25/00; A61P25/02; A61P25/28; A61P29/00; A61P41/00; A61P43/00; C07C275/32; C07C275/34; C07C275/36; C07C275/38; C07C275/40; C07C275/42; C07C323/44; C07D209/88; C07D213/40; C07D213/75; C07D215/38; C07D231/56; C07D307/52; C07D317/66; C07D333/20; C07D333/36; (IPC1-7): C07C275/32; A61K31/17; A61K31/245; A61K31/277; A61K31/341; A61K31/36; A61K31/381; A61K31/403; A61K31/416; A61K31/4406; A61K31/4409; A61K31/451; A61K31/47; A61P9/00; A61P9/10; A61P13/02; A61P13/10; A61P19/02; A61P25/00; A61P25/02; A61P25/28; A61P29/00; A61P41/00; A61P43/00; C07C275/34; C07C275/36; C07C275/38; C07C275/40; C07C275/42; C07C323/44; C07D209/88; C07D213/40; C07D213/75; C07D215/38; C07D231/56; C07D295/12; C07D307/52; C07D317/66; C07D333/20; C07D333/36

Attorney, Agent or Firm:

Ikeuchi, Sato & Partners

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