Title:
PRODUCTION OF ARYLOXYALKYLAMINO BENZOIC ACID AND ESTER
Document Type and Number:
Japanese Patent JPS5273834
Kind Code:
A
Abstract:
Procedure for the preparation of aryloxyalkylaminobenzoz acids and esters, of formula ** (Formula) ** where Y is straight or branched chain alkyl, CnH2n where n is 2 to 12; R1 is hydrogen, lower alkyl, 0, 2, 3-dihydroxypropyl; X is phenyl, naphthyl, thienyl, furyl, 1,2,3,4-tetrahydronaphthyl, 4-chloro-1-naphthyl, or substituted phenyl, wherein the phenyl substituents are halogen, hydroxyl, lower alkoxy, lower aralkyl, cyano, trihalomethyl, amino, lower alkanoylamino, lower alkylamino, dialkylamino lower, phenoxy, p-chlorophenoxy, benzyl-p-chlorobenzyloxy or cycloalkyl; and when R1 is hydrogen, the alkali metal salts or organic bases thereof; characterized in that it comprises reacting a lower alkyl p-aminobenzoate, p-aminobenzoic acid, or other ester of p-aminobenzoic acid with an alkylating agent, with or without a solvent, at 50º to 170ºC for 1 to 25 hours. (Machine-translation by Google Translate, not legally binding)
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Inventors:
JIEI DONARUDO ARUBURAITO
TOOMASU GEARII MAINAA
ROBAATO GOODON SHIEPAADO
TOOMASU GEARII MAINAA
ROBAATO GOODON SHIEPAADO
Application Number:
JP14827576A
Publication Date:
June 21, 1977
Filing Date:
December 09, 1976
Export Citation:
Assignee:
AMERICAN CYANAMID CO
International Classes:
A61K31/197; A61K31/34; A61K31/341; A61K31/38; A61K31/381; A61K31/445; A61P3/06; A61P9/10; A61K31/245; C07C59/68; C07C67/00; C07C219/34; C07C227/00; C07C227/04; C07C227/18; C07C227/20; C07C229/60; C07C309/66; C07D211/22; C07D307/58; C07D333/16; C07D333/20; C07D333/32; (IPC1-7): A61K31/245; A61K31/34; A61K31/38; A61K31/445; C07C101/62; C07D211/22; C07D307/58; C07D333/32