Title:
アミド反応用反応剤及びそれを用いたアミド化合物の製造方法
Document Type and Number:
Japanese Patent JP7244134
Kind Code:
B2
Abstract:
[Problem] To provide a novel means capable of generating highly stereoselective and/or highly efficient amidation reactions in a variety of substrates having a carboxyl group and an amino group, and capable of producing amide compounds.[Solution] A reaction agent for amide reactions between carboxyl groups and amino groups and including a silane compound indicated by general formula (A) and/or general formula (B).(In general formulas (A) and (B), each substituent represents the definition described in the Claims.)
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Inventors:
Yamamoto Takashi
Wataru Muramatsu
Michihiro Hattori
Wataru Muramatsu
Michihiro Hattori
Application Number:
JP2021553744A
Publication Date:
March 22, 2023
Filing Date:
October 30, 2020
Export Citation:
Assignee:
Chubu University
International Classes:
C07C231/02; C07C221/00; C07C233/05; C07C233/18; C07C233/22; C07C237/12; C07C237/20; C07D223/12; C07F7/04; C07F7/10; C07K1/02; C07K1/08
Other References:
第5版 実験化学講座 16,丸善株式会社,2005年,pp. 259-260, 268-269
SCHMIDT, Michael A. et al.,Development of a Two-Step, Enantioselective Synthesis of an Amino Alcohol Drug Candidate,Organic Process Research & Development,2015年,Vol. 19, No. 9,pp. 1317-1322,ISSN 1083-6160
MURAMATSU, Wataru et al.,Substrate-Directed Lewis-Acid Catalysis for Peptide Synthesis,Journal of the American Chemical Society,2019年07月16日,Vol. 141, No. 31,pp. 12288-12295,ISSN 1520-5126
MURAMATSU, Wataru et al.,Peptide bond-forming reaction via amino acid silyl esters: New catalytic reactivity of an aminosilan,ACS Catalysis,2020年,Vol. 10, No. 16,pp. 9594-9603
TOZAWA, Takashi et al.,An efficient method for the preparation of carboxamides by dehydration condensation using tetrakis(1,Chemistry Letters,2005年,Vol. 34, No. 12,pp. 1586-1587,ISSN 0366-7022
TOZAWA, Takashi et al.,A convenient method for preparations of 1-acylimidazoles and carboxamides by using novel imidazolyls,Chemistry Letters,2005年,Vol. 34, No. 5,pp. 734-735,ISSN 0366-7022
SCHMIDT, Michael A. et al.,Development of a Two-Step, Enantioselective Synthesis of an Amino Alcohol Drug Candidate,Organic Process Research & Development,2015年,Vol. 19, No. 9,pp. 1317-1322,ISSN 1083-6160
MURAMATSU, Wataru et al.,Substrate-Directed Lewis-Acid Catalysis for Peptide Synthesis,Journal of the American Chemical Society,2019年07月16日,Vol. 141, No. 31,pp. 12288-12295,ISSN 1520-5126
MURAMATSU, Wataru et al.,Peptide bond-forming reaction via amino acid silyl esters: New catalytic reactivity of an aminosilan,ACS Catalysis,2020年,Vol. 10, No. 16,pp. 9594-9603
TOZAWA, Takashi et al.,An efficient method for the preparation of carboxamides by dehydration condensation using tetrakis(1,Chemistry Letters,2005年,Vol. 34, No. 12,pp. 1586-1587,ISSN 0366-7022
TOZAWA, Takashi et al.,A convenient method for preparations of 1-acylimidazoles and carboxamides by using novel imidazolyls,Chemistry Letters,2005年,Vol. 34, No. 5,pp. 734-735,ISSN 0366-7022
Attorney, Agent or Firm:
Aoki Atsushi
Shinji Mihashi
Nakajima Masaru
Youichi Watanabe
Nobuo Sekine
Shinji Mihashi
Nakajima Masaru
Youichi Watanabe
Nobuo Sekine