Title:
一時的な不死化
Document Type and Number:
Japanese Patent JP2005506090
Kind Code:
A
Abstract:
The invention relates to a method for transiently immortalizing cells according to which immortalization proteins are introduced into the cells from outside. The invention also relates to a method for producing cells according to which organ-related cells are transiently immortalized by the exogenous supply of immortalization proteins and are remortalized after their expansion. The invention further relates to the cells produced according to the inventive method, to the use of said cells for producing a transplant and to the immortalization proteins used in the method.
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Inventors:
Cupel, Yang-Heiner
Meyer, Ralph
Myer-Ficca, Mirella
Kuhn, Anne
Meyer, Ralph
Myer-Ficca, Mirella
Kuhn, Anne
Application Number:
JP2003538384A
Publication Date:
March 03, 2005
Filing Date:
October 07, 2002
Export Citation:
Assignee:
Heart Biosystems Gambaver
International Classes:
C12N15/09; A61K35/12; A61K38/00; A61L27/00; A61P43/00; C07K14/025; C07K14/035; C07K14/47; C07K14/705; C07K16/18; C07K19/00; C12N5/0775; C12N5/10; C12N9/12; (IPC1-7): C12N15/09; A61K35/12; A61K38/00; A61L27/00; A61P43/00; C07K14/47; C07K14/705; C07K16/18; C07K19/00; C12N5/10
Attorney, Agent or Firm:
Takehiko Suzue
Satoshi Kono
Makoto Nakamura
Kurata Masatoshi
Takashi Mine
Yoshihiro Fukuhara
Sadao Muramatsu
Ryo Hashimoto
Satoshi Kono
Makoto Nakamura
Kurata Masatoshi
Takashi Mine
Yoshihiro Fukuhara
Sadao Muramatsu
Ryo Hashimoto