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Title:
TETRACYCLINE DERIVATIVE FOR TREATMENT OF BACTERIA INFECTION, VIRUS INFECTION AND PARASITE INFECTION
Document Type and Number:
Japanese Patent JP2015205939
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a tetracycline derivative for treatment of bacteria infection, virus infection and parasite infection.SOLUTION: The invention at least partially relates to a substituted tetracycline compound of the formula (I), where X is CHC(RY'Y), CRR, C=CRR, S, NRor O, E is NRR, ORor (CH)C(=W')WR, W is O, S, NRor CRR, W' is O, S or NR. These tetracycline compounds can be used for treating many tetracycline compound-responsive conditions, for example bacteria infections and neoplasm.

Inventors:
ABATO PAUL
ASSEFA HAREGEWEIN
BERNIAC JOEL
BHATIA BEENA
BOWSER TODD
GRIER MARK
HONEYMAN LAURA
ISMAIL MOHAMED
KIM OAK K
NELSON MARK
PAN JINGWEN
VERMA ATUL
Application Number:
JP2015160343A
Publication Date:
November 19, 2015
Filing Date:
August 17, 2015
Export Citation:
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Assignee:
PARATEK PHARM INNC
International Classes:
C07C237/26; A61K31/166; A61K31/216; A61K31/277; A61K31/341; A61K31/351; A61K31/40; A61K31/4035; A61K31/415; A61K31/417; A61K31/42; A61K31/421; A61K31/426; A61K31/435; A61K31/445; A61K31/47; A61K31/495; A61K31/4965; A61K31/505; A61K31/535; A61K31/5375; A61P17/00; A61P25/00; A61P29/00; A61P31/04; A61P31/12; A61P33/00; C07C239/20; C07C243/12; C07C243/18; C07C255/59; C07C259/10; C07C271/22; C07D207/20; C07D207/337; C07D209/44; C07D211/14; C07D211/18; C07D211/70; C07D213/64; C07D215/14; C07D231/12; C07D233/64; C07D239/26; C07D241/12; C07D261/02; C07D261/04; C07D261/08; C07D263/32; C07D265/02; C07D271/06; C07D277/30; C07D295/02; C07D295/12; C07D295/16; C07D307/22; C07D307/54; C07D309/22
Domestic Patent References:
JP5583411B22014-09-03
JP2004502753A2004-01-29
JP2005514410A2005-05-19
JP2006503898A2006-02-02
Foreign References:
WO2004064728A22004-08-05
WO2005009943A22005-02-03
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto