イミダゾール化合物およびそのアデノシンデアミナーゼ阻害剤としての使用

Title:

イミダゾール化合物およびそのアデノシンデアミナーゼ阻害剤としての使用

Document Type and Number:

Japanese Patent JP4788860

Kind Code:

B2

Abstract:

Imidazole compounds having adenosine deaminase inhibitory activity represented by the formula (I) wherein R¹is aryloxy, or aryl which is optionally substituted with suitable substituent(s); R²is lower alkyl; R³is hydroxy or protected hydroxy; and -A- is lower alkylene, its prodrug, or their salt. The compounds are useful for treating and/or preventing diseases for which adenosine is effective.

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Inventors:

Kira Tsuji
Terasaka
Katsuya Nakamura

Application Number:

JP2001553273A

Publication Date:

October 05, 2011

Filing Date:

January 19, 2001

Export Citation:

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Assignee:

Astellas Pharma Inc.

International Classes:

A61K31/4164; C07D233/90; A61K31/4178; A61K31/4245; A61K31/427; A61K31/4439; A61P9/10; A61P29/00; A61P35/02; A61P37/02; A61P37/06; A61P43/00; C07D233/64; C07D401/12; C07D403/12; C07D403/14; C07D409/12; C07D409/14; C07D413/12; C07D417/12; C07D417/14

Domestic Patent References:

JP2002521369A

2002-07-16

Foreign References:

WO1998002166A1

1998-01-22

Attorney, Agent or Firm:

Hatsushi Shimizu
Kazunori Hashimoto

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