Title:
A calcium antagonist / angiotensin II receptor antagonist content medicine tablet
Document Type and Number:
Japanese Patent JP6231959
Kind Code:
B2
Abstract:
Provided is a pharmaceutical preparation containing a calcium antagonist and an angiotensin II receptor antagonist as active ingredients, and containing 5 mass% or more of a disintegrant, the pharmaceutical preparation being characterized in that at least the calcium antagonist has the form of a solid dispersion. The pharmaceutical preparation improves the storage stability of the angiotensin II receptor antagonist. The pharmaceutical preparation has an elution profile similar to those of commercially available calcium antagonist preparations and commercially available angiotensin II receptor antagonist preparations.
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Inventors:
Yukiko Tanaka
Ichiro Hara
Yuyuki Higuchi
Tomoya Onoshita
Teramoto Akiko
Ichiro Hara
Yuyuki Higuchi
Tomoya Onoshita
Teramoto Akiko
Application Number:
JP2014182380A
Publication Date:
November 15, 2017
Filing Date:
September 08, 2014
Export Citation:
Assignee:
ea pharma corporation
International Classes:
A61K31/4422; A61K9/10; A61K9/16; A61K9/20; A61K9/30; A61K9/48; A61K31/41; A61K47/02; A61K47/26; A61K47/34; A61K47/38; A61P9/12
Domestic Patent References:
| JP2008044871A | ||||
| JP3110794B2 | ||||
| JP2009521526A | ||||
| JP2008081512A | ||||
| JP2003104888A | ||||
| JP2008133258A |
Foreign References:
| WO2012063498A1 | ||||
| WO2014058047A1 |
Other References:
薬学雑誌,2004年,vol.124, no.1,p.19-23
Attorney, Agent or Firm:
Takaki Nishijima
Disciple Maru Ken
Shinichiro Tanaka
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Yasushi Sasaki
Disciple Maru Ken
Shinichiro Tanaka
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Yasushi Sasaki