Title:
画像誘導組織切除を改善するための装置
Document Type and Number:
Japanese Patent JP4929159
Kind Code:
B2
Abstract:
The cryosurgical kit and method of use relates to the combined use of biodegradable, imageable, drug(s) carriers, vectors or microcapsules deposited into a target tissue region inside a body and the controlled cooling of the target tissue region. A minimally invasive method of treatment that applies a cooling device to a selected tissue region, uses a vibrating resonant frequency delivery device to inject drug(s) carriers (microcapsules) containing therapeutic and contrast agents into tissue region(s) submitted to cooling temperatures, successive real-time imaging of the microcapsule deposition and later detection of the progressive degradation of microcapsules with ultrasound imaging which provides estimation of sustained release rates and for planning re-dosing regimens. The thermosensitive microcapsules preferably contain ethiodol, a contrast agent for Ultrasound and/or X-Ray imaging, and cytotoxic drug (s).
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Inventors:
Repivato, patrick
Kolasinsky, Roger
Kolasinsky, Roger
Application Number:
JP2007508375A
Publication Date:
May 09, 2012
Filing Date:
March 31, 2005
Export Citation:
Assignee:
Neuve Therapeutics, Inc.
International Classes:
A61B18/02; A61B19/00; A61K9/50; A61K31/513; A61K49/04; A61M25/00; A61P35/00; A61N7/00
Domestic Patent References:
| JP2000513963A | 2000-10-24 | |||
| JPH07213622A | 1995-08-15 | |||
| JPH03297475A | 1991-12-27 |
Foreign References:
| US6391026B1 | 2002-05-21 | |||
| WO2002045609A1 | 2002-06-13 | |||
| WO2004012616A1 | 2004-02-12 | |||
| WO2002078611A2 | 2002-10-10 |
Attorney, Agent or Firm:
Kazunori Saito