Title:
新規なN-ヒドロキシチオウレア、ウレア及びアミド化合物とこれらからなる薬剤組成物
Document Type and Number:
Japanese Patent JP2006503090
Kind Code:
A
Abstract:
The present invention relates to novel n-hydroxythiourea, urea and amide compounds as a potent vanilloid receptor antagonist and the pharmaceutical compositions comprising the same. The inventive compound can be useful for analgesics to prevent, alleviate or treat pain diseases or inflammatory disease comprising pain, acute pain, chronic pain, neuropathic pain, post-operative pain, migraine, arthralgia, neuropathies, nerve injury, diabetic neuropathy, neurodegeneration, neurotic skin disorder, stroke, urinary bladder hypersensitiveness, irritable bowel syndrome, a respiratory disorder such as asthma or chronic obstructive pulmonary disease, irritation of skin, eye or mucous membrane, fervescence, stomach-duodenal ulcer, inflammatory bowel disease, inflammatory disease and urgent urinary incontinence.
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Inventors:
Lee, Jew
Application Number:
JP2004545059A
Publication Date:
January 26, 2006
Filing Date:
October 17, 2003
Export Citation:
Assignee:
Digital Biotech Company Limited
International Classes:
C07C311/08; C07C327/38; A61K31/18; A61K31/222; A61P1/00; A61P1/04; A61P11/06; A61P11/08; A61P13/10; A61P13/12; A61P17/00; A61P19/02; A61P25/00; A61P25/06; A61P25/08; A61P29/00; A61P43/00; C07C259/06; C07C275/64; C07C311/19; C07C335/04; C07C335/42
Attorney, Agent or Firm:
▲吉▼川 俊雄