Title:
ACETOHYDROXY ACID SYNTHASE MUTANT AND METHOD FOR PRODUCING MICROORGANISM COMPRISING SAME OR L-BRANCHED CHAIN AMINO ACID USING SAME
Document Type and Number:
WIPO Patent Application WO/2019/013532
Kind Code:
A3
Abstract:
The present application relates to a novel acetohydroxy acid synthetase mutant, and a method for producing a microorganism comprising the same or an L-branched chain amino acid using the same.
Inventors:
JEON AE JI (KR)
SONG BYEONG CHEOL (KR)
LEE JI HYE (KR)
KIM JONG HYUN (KR)
KIM HYE WON (KR)
SONG BYEONG CHEOL (KR)
LEE JI HYE (KR)
KIM JONG HYUN (KR)
KIM HYE WON (KR)
Application Number:
PCT/KR2018/007821
Publication Date:
April 04, 2019
Filing Date:
July 10, 2018
Export Citation:
Assignee:
CJ CHEILJEDANG CORP (KR)
International Classes:
C12N9/10; C12N15/77; C12P13/04
Domestic Patent References:
| WO2014142463A1 | 2014-09-18 |
Foreign References:
| KR101720836B1 | 2017-04-03 | |||
| US20140335574A1 | 2014-11-13 |
Other References:
IBDAH, MUHAMMAD ET AL.: "Homology Modeling of the Structure of Bacterial Acetohydroxy Acid Synthase and Examination of the Active Site by Site-directed Mutagenesis", BIOCHEMISTRY, vol. 35, no. 50, 1 January 1996 (1996-01-01), pages 16282 - 16291, XP055615152, ISSN: 0006-2960, DOI: 10.1021/bi961588i
CHIPMAN, DAVID ET AL.: "Biosynthesis of 2-aceto-2-hydroxy Acids: Acetolactate Synthases and Acetohydroxyacid Synthases", BIOCHIMICA ET BIOPHYSICA ACTA (BBA)-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY, vol. 1385, no. 2, 1998, pages 401 - 419, XP004278425
CHIPMAN, DAVID ET AL.: "Biosynthesis of 2-aceto-2-hydroxy Acids: Acetolactate Synthases and Acetohydroxyacid Synthases", BIOCHIMICA ET BIOPHYSICA ACTA (BBA)-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY, vol. 1385, no. 2, 1998, pages 401 - 419, XP004278425
Attorney, Agent or Firm:
SON, Min (KR)
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