ACYL- PHOSPHATE AND PHOSPHONATE PROBES AND METHODS OF THEIR SYNTHESIS AND USE IN PROTEOMIC ANALYSIS

WIPO Patent Application WO2004090154

A3

The present invention provides tagged acyl phosphate probes ("TAPPs"), and methods of their preparation and use. The subject methods and compositions can provide enhanced simplicity and accuracy in identifying changes in the presence, amount, or activity of target proteins in a complex protein mixture, preferably nucleotide binding proteins using nucleotide binding protein-directed TAPPs. The profiling methods described herein can have a number of steps leading to the identification of target nucleotide binding protein(s) in a complex protein mixture.

JPH06228176	NEW HALOGENATED CYCLOALKANECARBOXAMIDE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT
WO/2001/044258	NOVEL HETEROCYCLES

CAMPBELL DAVID ALAN (US)
LIYANAGE MAREK (US)
SZARDENINGS ANNA KATRIN (US)
WU MIN (US)

PCT/US2004/010075

May 06, 2005

April 01, 2004

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ACTIVX BIOSCIENCES INC (US)
CAMPBELL DAVID ALAN (US)
LIYANAGE MAREK (US)
SZARDENINGS ANNA KATRIN (US)
WU MIN (US)

C07F9/6512; C07H19/10; C07H19/20; C07H21/04; C07K9/00; C12Q1/68; C12Q; (IPC1-7): C12Q1/68

MADOYAN I.A. ET AL.: "Affinity labelling of tryptophanyl-tRNA synthetase with mesitoyl-AMP", vol. 123, January 1981 (1981-01-01), pages 156 - 160, XP008045403
MANABE S. ET AL.: "Preparation of glycosylated amino acid derivatives for glycoprotein synthesis by in vitro transaltion system", BIOORG. MED. CHEM., vol. 10, May 2002 (2002-05-01), pages 573 - 581, XP002985472
"6-carboxfluorescein-ON phosporamidite user manual", CLONOTECH CATALOG, 1999, XP002985473

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