Title:
AMELIORATING AGENT OR PROPHYLACTIC AGENT FOR MUSCLE WEAKNESS SYMPTOM IN DISEASE OR SYNDROME ASSOCIATED WITH METABOLIC DISORDER
Document Type and Number:
WIPO Patent Application WO/2022/004788
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing an ameliorating agent or a prophylactic agent for a muscle weakness symptom in a disease or a syndrome associated with a metabolic disorder. The present invention provides an ameliorating agent or a prophylactic agent for a muscle weakness symptom in a disease or a syndrome associated with a metabolic disorder, the agent containing a compound having a morphinan backbone structure typified by the below-mentioned compound or a pharmacologically acceptable acid addition salt thereof as an active ingredient.
Inventors:
OMORI YU (JP)
UCHIDA MASASHI (JP)
UCHIDA MASASHI (JP)
Application Number:
PCT/JP2021/024759
Publication Date:
January 06, 2022
Filing Date:
June 30, 2021
Export Citation:
Assignee:
TORAY INDUSTRIES (JP)
International Classes:
A61K31/485; A61P3/00; A61P21/00
Domestic Patent References:
| WO1993015081A1 | 1993-08-05 | |||
| WO2015166887A1 | 2015-11-05 | |||
| WO2002066475A2 | 2002-08-29 | |||
| WO1993015081A1 | 1993-08-05 | |||
| WO1998023290A1 | 1998-06-04 | |||
| WO2012105475A1 | 2012-08-09 | |||
| WO2016152965A1 | 2016-09-29 |
Foreign References:
| JP2017520622A | 2017-07-27 | |||
| JP2020112486A | 2020-07-27 | |||
| JP2021097684A | 2021-07-01 |
Other References:
YOUNG JESSICA C, JONSSON FUNK MICHELE, DASGUPTA NABARUN: "Medical Use of Long-term Extended-release Opioid Analgesics in Commercially Insured Adults in the United States", PAIN MEDICINE, BLACKWELL SCIENCE, MALDEN, US, vol. 21, no. 4, 1 April 2020 (2020-04-01), US , pages 724 - 735, XP055895793, ISSN: 1526-2375, DOI: 10.1093/pm/pnz155
O'BRIEN T., CHRISTRUP L.L., DREWES A.M., FALLON M.T., KRESS H.G., MCQUAY H.J., MIKUS G., MORLION B.J., PEREZ-CAJARAVILLE J., POGAT: "European Pain Federation position paper on appropriate opioid use in chronic pain management", EUROPEAN JOURNAL OF PAIN, SAUNDERS, LONDON, GB, vol. 21, no. 1, 1 January 2017 (2017-01-01), GB , pages 3 - 19, XP055895794, ISSN: 1090-3801, DOI: 10.1002/ejp.970
LYNCH ET AL., PHARMACOLOGY & THERAPEUTICS, vol. 113, 2007, pages 461 - 487
CRUZ-JENTOFT ET AL., AGE AND AGEING, vol. 43, 2014, pages 748 - 759
CHRONIC RESPIRATORY DISEASE, vol. 11, 2014, pages 247 - 255
THE JOURNAL OF PHYSIOLOGY, vol. 574, 2006, pages 85 - 93
JOURNAL OF JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE, vol. 46, 1993, pages 451 - 458
THE AMERICAN JOURNAL OF CLINICAL NUTRITION, vol. 97, 2013, pages 7 - 14
SCIENCE ADVANCES, vol. 5, 2019, pages eaau7802
LIPIDS, vol. 48, 2013, pages 1135 - 1143
ONCOLOGY REPORTS, vol. 25, 2011, pages 189 - 193
JOURNAL OF APPLIED PHYSIOLOGY, vol. 126, 2019, pages 170 - 182
DISEASE MODELS & MECHANISMS, vol. 10, 2017, pages 787 - 796
BIOSCIENCE, vol. 29, 1979, pages 168 - 172
JOURNAL OF PHYSICAL THERAPY SCIENCE, vol. 26, 2011, pages 255 - 258
ANNALS OF REHABILITATION MEDICINE, vol. 41, 2017
JOURNAL OF CACHEXIA, SARCOPENIA AND MUSCLE, vol. 9, 2018, pages 975 - 986
NEUROTOXICOLOGY AND TERATOLOG, vol. 25, 2003, pages 543 - 553
THE LANCET ONCOLOGY, vol. 17, 2016, pages 519 - 531
THE LANCET ONCOLOGY, vol. 14, 2013, pages 335 - 345
O'BRIEN T., CHRISTRUP L.L., DREWES A.M., FALLON M.T., KRESS H.G., MCQUAY H.J., MIKUS G., MORLION B.J., PEREZ-CAJARAVILLE J., POGAT: "European Pain Federation position paper on appropriate opioid use in chronic pain management", EUROPEAN JOURNAL OF PAIN, SAUNDERS, LONDON, GB, vol. 21, no. 1, 1 January 2017 (2017-01-01), GB , pages 3 - 19, XP055895794, ISSN: 1090-3801, DOI: 10.1002/ejp.970
LYNCH ET AL., PHARMACOLOGY & THERAPEUTICS, vol. 113, 2007, pages 461 - 487
CRUZ-JENTOFT ET AL., AGE AND AGEING, vol. 43, 2014, pages 748 - 759
CHRONIC RESPIRATORY DISEASE, vol. 11, 2014, pages 247 - 255
THE JOURNAL OF PHYSIOLOGY, vol. 574, 2006, pages 85 - 93
JOURNAL OF JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE, vol. 46, 1993, pages 451 - 458
THE AMERICAN JOURNAL OF CLINICAL NUTRITION, vol. 97, 2013, pages 7 - 14
SCIENCE ADVANCES, vol. 5, 2019, pages eaau7802
LIPIDS, vol. 48, 2013, pages 1135 - 1143
ONCOLOGY REPORTS, vol. 25, 2011, pages 189 - 193
JOURNAL OF APPLIED PHYSIOLOGY, vol. 126, 2019, pages 170 - 182
DISEASE MODELS & MECHANISMS, vol. 10, 2017, pages 787 - 796
BIOSCIENCE, vol. 29, 1979, pages 168 - 172
JOURNAL OF PHYSICAL THERAPY SCIENCE, vol. 26, 2011, pages 255 - 258
ANNALS OF REHABILITATION MEDICINE, vol. 41, 2017
JOURNAL OF CACHEXIA, SARCOPENIA AND MUSCLE, vol. 9, 2018, pages 975 - 986
NEUROTOXICOLOGY AND TERATOLOG, vol. 25, 2003, pages 543 - 553
THE LANCET ONCOLOGY, vol. 17, 2016, pages 519 - 531
THE LANCET ONCOLOGY, vol. 14, 2013, pages 335 - 345
Attorney, Agent or Firm:
HIRAKI & ASSOCIATES (JP)
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