Title:
ANALYSIS METHOD
Document Type and Number:
WIPO Patent Application WO/2023/100567
Kind Code:
A1
Abstract:
In this analysis method, fusions (1A, 1B, 1C) comprising labels (5A, 5B, 5C) and first bonding substances (3A, 3B, 3C) that have activity of bonding with target substances (7A, 7B, 7C) are mixed with a specimen, thereby generating a mixture (21). The mixture is put into contact with second bonding substances (19, 19A, 19B, 19C) fixed to a base (12). The phenomenon of a fusion bonded to a target substance which is bonded with a second bonding substance coming into being is detected. Each of the first bonding substances is a substance composed of a nucleic acid or a substance composed of an amino acid. The base is provided in each of a plurality of regions (17A, 17B, 17C). Per each region, the target substance that the second bonding substance bonds with differs.
Inventors:
HAYAKAWA KEI (JP)
ASANO MANA (JP)
NUKAZUKA AKIRA (JP)
NAKAGAWA KAZUHISA (JP)
NIIMOTO MAI (JP)
KANO KAZUHIKO (JP)
ASANO MANA (JP)
NUKAZUKA AKIRA (JP)
NAKAGAWA KAZUHISA (JP)
NIIMOTO MAI (JP)
KANO KAZUHIKO (JP)
Application Number:
PCT/JP2022/040458
Publication Date:
June 08, 2023
Filing Date:
October 28, 2022
Export Citation:
Assignee:
DENSO CORP (JP)
International Classes:
C12Q1/68; G01N33/543
Foreign References:
| JP2019033750A | 2019-03-07 |
Other References:
SOSIC ALICE, MENEGHELLO ANNA, ANTOGNOLI AGNESE, CRETAIO ERICA, GATTO BARBARA: "Development of a Multiplex Sandwich Aptamer Microarray for the Detection of VEGF165 and Thrombin", SENSORS, vol. 13, no. 10, pages 13425 - 13438, XP093069673, DOI: 10.3390/s131013425
SARAF NILESHI, VILLEGAS MICHAEL, WILLENBERG BRADLEY JAY, SEAL SUDIPTA: "Multiplex Viral Detection Platform Based on a Aptamers-Integrated Microfluidic Channel", ACS OMEGA, ACS PUBLICATIONS, US, vol. 4, no. 1, 31 January 2019 (2019-01-31), US , pages 2234 - 2240, XP093069675, ISSN: 2470-1343, DOI: 10.1021/acsomega.8b03277
ANAL. CHEM., vol. 92, 2020, pages 9895 - 9900
CHEM. COMMUN., vol. 56, 2020, pages 10235 - 10238
ANGEW. CHEM., vol. 133, 2021, pages 10367 - 10373
SARAF NILESHI, VILLEGAS MICHAEL, WILLENBERG BRADLEY JAY, SEAL SUDIPTA: "Multiplex Viral Detection Platform Based on a Aptamers-Integrated Microfluidic Channel", ACS OMEGA, ACS PUBLICATIONS, US, vol. 4, no. 1, 31 January 2019 (2019-01-31), US , pages 2234 - 2240, XP093069675, ISSN: 2470-1343, DOI: 10.1021/acsomega.8b03277
ANAL. CHEM., vol. 92, 2020, pages 9895 - 9900
CHEM. COMMUN., vol. 56, 2020, pages 10235 - 10238
ANGEW. CHEM., vol. 133, 2021, pages 10367 - 10373
Attorney, Agent or Firm:
NAGOYA INTERNATIONAL IP FIRM (JP)
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