Title:
ARRAY FOR DETECTING GENE MUTATION AND DETECTION METHOD
Document Type and Number:
WIPO Patent Application WO/2007/055244
Kind Code:
A1
Abstract:
By combining a first group of probe spots with a second group of probe spots, it becomes possible to accurately detect a gene mutation, in particular, a gene relating to the drug sensitivity or drug tolerance to chronic myelocytic leukemia. Use of this array for detecting gene mutation makes it possible to accurately detect such a gene as described above.
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Inventors:
NAOE TOMOKI (JP)
YOSHIDA YASUKO (JP)
YAMADA KAZUNARI (JP)
NIWA KOUSUKE (JP)
YOSHIDA YASUKO (JP)
YAMADA KAZUNARI (JP)
NIWA KOUSUKE (JP)
Application Number:
PCT/JP2006/322280
Publication Date:
May 18, 2007
Filing Date:
November 08, 2006
Export Citation:
Assignee:
UNIV NAGOYA NAT UNIV CORP (JP)
NGK INSULATORS LTD (JP)
NAOE TOMOKI (JP)
YOSHIDA YASUKO (JP)
YAMADA KAZUNARI (JP)
NIWA KOUSUKE (JP)
NGK INSULATORS LTD (JP)
NAOE TOMOKI (JP)
YOSHIDA YASUKO (JP)
YAMADA KAZUNARI (JP)
NIWA KOUSUKE (JP)
International Classes:
C12N15/09; C12Q1/68; G01N37/00
Domestic Patent References:
| WO2005090565A1 | 2005-09-29 |
Other References:
KIYOI J. ET AL.: "BCR-ABL Yosei Hakketsubyo ni Okeru Imatinib Taisei", CANCER FRONTIER, vol. 6, no. 1, 2004, pages 48 - 55, XP003012782
TAUCHI T. ET AL.: "Kobetsuka Iryo no Jitsugen o Mezashite Mansei Kotsuzuisei Hakketsubyo no Saihatsu to Imatinib Taisei Kiko", MOLECULAR MEDICINE, vol. 42, no. 8, 25 July 2005 (2005-07-25), pages 873 - 878, XP003012783
AZAM M. ET AL.: "Mechanism of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL", CELL, vol. 112, no. 6, 2003, pages 831 - 843, XP003012784
MIYAZAWA K.: "Hakketsubyo.Lymph-shu.Kotsuzuishu.Chiryo/Genchi Ika ga Shitte Okubeki Saishin no Chiryoho to Sono Seika Imatinib ni yoru Mansei Kotsuzuisei Hakketsubyo no Chiryo-Sono Tekisei na Shiyoho to Taisei CML eno Taisaku", MEDICAL PRACTICE, vol. 22, no. 8, 1 August 2005 (2005-08-01), pages 1385 - 1390, XP003012785
TAUCHI T. ET AL.: "Kobetsuka Iryo no Jitsugen o Mezashite Mansei Kotsuzuisei Hakketsubyo no Saihatsu to Imatinib Taisei Kiko", MOLECULAR MEDICINE, vol. 42, no. 8, 25 July 2005 (2005-07-25), pages 873 - 878, XP003012783
AZAM M. ET AL.: "Mechanism of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL", CELL, vol. 112, no. 6, 2003, pages 831 - 843, XP003012784
MIYAZAWA K.: "Hakketsubyo.Lymph-shu.Kotsuzuishu.Chiryo/Genchi Ika ga Shitte Okubeki Saishin no Chiryoho to Sono Seika Imatinib ni yoru Mansei Kotsuzuisei Hakketsubyo no Chiryo-Sono Tekisei na Shiyoho to Taisei CML eno Taisaku", MEDICAL PRACTICE, vol. 22, no. 8, 1 August 2005 (2005-08-01), pages 1385 - 1390, XP003012785
Attorney, Agent or Firm:
ITEC INTERNATIONAL PATENT FIRM (9-26 Sakae 2-chome, Naka-k, Nagoya-shi Aichi 08, JP)
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