Title:
BENZYL PHENYL ETHER DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/202273
Kind Code:
A1
Abstract:
Disclosed in the present invention are a benzyl phenyl ether derivative, a preparation method therefor, and a pharmaceutical composition and uses thereof. Specifically, the present invention relates to a benzyl phenyl ether derivative represented by formula I, a pharmaceutically-acceptable salt thereof, a stereoisomer thereof, a preparation method therefor, and a pharmaceutical composition containing the one or more compounds, and uses of the compounds in treating diseases related to PD-1/PD-L1 signal channels, such as cancers, infectious diseases and autoimmune diseases.
Inventors:
FENG ZHIQIANG (CN)
CHEN XIAOGUANG (CN)
YANG YANG (CN)
LAI FANGFANG (CN)
JI MING (CN)
ZHANG LIJING (CN)
ZHENG YI (CN)
XUE NINA (CN)
WANG KE (CN)
LI LING (CN)
CHEN XIAOGUANG (CN)
YANG YANG (CN)
LAI FANGFANG (CN)
JI MING (CN)
ZHANG LIJING (CN)
ZHENG YI (CN)
XUE NINA (CN)
WANG KE (CN)
LI LING (CN)
Application Number:
PCT/CN2017/085417
Publication Date:
November 30, 2017
Filing Date:
May 23, 2017
Export Citation:
Assignee:
INST MATERIA MEDICA CAMS (CN)
International Classes:
C07C255/54; C07C233/36; C07C311/05; C07D319/18; C07D405/12; A61K31/165; A61K31/277; A61K31/36; A61P31/00; A61P35/00; A61P37/00
Domestic Patent References:
| WO2015034820A1 | 2015-03-12 |
Foreign References:
| US20150291549A1 | 2015-10-15 |
Other References:
See also references of EP 3450423A4
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