Title:
BIO-ARTIFICIAL SUBSTRATE FOR THE PRODUCTION OF ANIMAL AND, IN PARTICULAR, HUMAN TISSUES AND ORGANS
Document Type and Number:
WIPO Patent Application WO2001025403
Kind Code:
A3
Abstract:
A substrate suitable for the survival, the proliferation and the correct differentiation and functioning of specialised tissue cells of the human and animal body, consisting of a material that is bio-compatible and bio-resorbable in pre-determinable times, which can be transplanted or implanted onto or connected with the body in order to achieve a complete integration of the transplanted, implanted or connected tissue with the other cell systems and their functions in the organism onto which the transplant or the implant or with which the connection has been made, and comprising a mixture and/or combination of natural and/or synthetic polymers in which fibroin is present.
Inventors:
ARMATO UBALDO (IT)
MIGLIARESI CLAUDIO (IT)
MOTTA ANTONELLA (IT)
MIGLIARESI CLAUDIO (IT)
MOTTA ANTONELLA (IT)
Application Number:
PCT/IT2000/000382
Publication Date:
November 08, 2001
Filing Date:
September 28, 2000
Export Citation:
Assignee:
CONSORZIO PER GLI STUDI UNI (IT)
ARMATO UBALDO (IT)
MIGLIARESI CLAUDIO (IT)
MOTTA ANTONELLA (IT)
ARMATO UBALDO (IT)
MIGLIARESI CLAUDIO (IT)
MOTTA ANTONELLA (IT)
International Classes:
A61L27/22; A61L27/36; A61L27/38; A61L27/60; C12N5/00; C12N5/08; A61K35/12; (IPC1-7): C12N5/06; C12N5/08
Domestic Patent References:
| WO1996025961A1 | 1996-08-29 |
Foreign References:
| US5902741A | 1999-05-11 | |||
| US5606019A | 1997-02-25 |
Other References:
SANTIN MATTEO ET AL: "In vitro evaluation of the inflammatory potential of the silk fibroin.", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, vol. 46, no. 3, pages 382 - 389, XP002166763, ISSN: 0021-9304
GOTOH YOHKO ET AL: "Effect of the chemical modification of the arginyl residue in Bombyx mori silk fibroin on the attachment and growth of fibroblast cells.", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, vol. 39, no. 3, 5 May 1998 (1998-05-05), pages 351 - 357, XP002166764, ISSN: 0021-9304
GOTOH YOHKO ET AL: "Effect of the chemical modification of the arginyl residue in Bombyx mori silk fibroin on the attachment and growth of fibroblast cells.", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, vol. 39, no. 3, 5 May 1998 (1998-05-05), pages 351 - 357, XP002166764, ISSN: 0021-9304
Download PDF: