Title:
METHODS FOR INHIBITING OSTEOCLAST FORMATION OR METHODS FOR INHIBITING BONE RESORPTION
Document Type and Number:
WIPO Patent Application WO/2001/025404
Kind Code:
A1
Abstract:
A method for inhibiting the formation of osteoclasts or a method for inhibiting bone resorption characterized by effecting UV irradiation in an incubation system containing osteoclast precursor cells and inducers in a liquid medium; or a method for inhibiting the formation of osteoclasts or a method for inhibiting bone resorption characterized by effecting UV irradiation in a co-incubation system containing osteoclast precursor cells and inducers in a liquid medium.
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Inventors:
AZUMA YOSHIAKI (JP)
OHTA TOMOHIRO (JP)
KOMORIYA KEIJI (JP)
KUDO AKIRA (JP)
TAKESHITA SUNAO (JP)
KAJI KEISUKE (JP)
OHTA TOMOHIRO (JP)
KOMORIYA KEIJI (JP)
KUDO AKIRA (JP)
TAKESHITA SUNAO (JP)
KAJI KEISUKE (JP)
Application Number:
PCT/JP2000/004146
Publication Date:
April 12, 2001
Filing Date:
June 23, 2000
Export Citation:
Assignee:
TEIJIN LTD (JP)
AZUMA YOSHIAKI (JP)
OHTA TOMOHIRO (JP)
KOMORIYA KEIJI (JP)
KUDO AKIRA (JP)
TAKESHITA SUNAO (JP)
KAJI KEISUKE (JP)
AZUMA YOSHIAKI (JP)
OHTA TOMOHIRO (JP)
KOMORIYA KEIJI (JP)
KUDO AKIRA (JP)
TAKESHITA SUNAO (JP)
KAJI KEISUKE (JP)
International Classes:
A61K31/59; A61K38/00; A61K38/22; A61K41/00; A61N7/00; A61P19/08; C12N5/078; (IPC1-7): C12N5/06
Domestic Patent References:
| WO1999067289A1 | 1999-12-29 |
Foreign References:
| EP0861663A2 | 1998-09-02 | |||
| EP0816380A1 | 1998-01-07 | |||
| JPH06141850A | 1994-05-24 |
Other References:
TAKAHASHI N. et al., "A New Member of Tumor Necrosis Factor Ligand Family, ODF/OPGL/TRANCE/RANKL, Regulates Osteoclast Differentiation and Function", Biochem. Biophys. Res. Commun. (March, 1999), Vol. 256, No. 3, pages 449-455.
Attorney, Agent or Firm:
Maeda, Sumihiro (Intellectual Property Center 1-1 Uchisaiwaicho
2-chome Chiyoda-ku, Tokyo, JP)
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