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Title:
CHEMICALLY MODIFIED PROTEIN AND PROCESS FOR ITS PREPARATION
Document Type and Number:
WIPO Patent Application WO/1985/003934
Kind Code:
A1
Abstract:
Chemically modified proteins wherein a group R-(OCH2CH2)n- (wherein R represents a terminal oxygen-protecting group, and n represents an arbitrary positive integer) is directly bound to at least one primary amino group of a physiologically active protein. They are useful as medicines, etc.

Inventors:
NISHIMURA OSAMU (JP)
FUJINO MASAHIKO (JP)
Application Number:
PCT/JP1984/000085
Publication Date:
September 12, 1985
Filing Date:
March 06, 1984
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Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD (JP)
International Classes:
A61K35/74; A61K38/00; A61K38/16; A61K38/21; A61K38/25; A61K38/28; C07K14/655; A61K38/31; A61K38/35; C07K1/107; C07K1/113; C07K14/00; C07K14/52; C07K14/54; C07K14/55; C07K14/555; C07K14/56; C07K14/57; C07K14/575; C07K14/585; C07K14/60; C07K14/62; C07K17/08; C08H1/00; C12N15/00; C12N15/09; (IPC1-7): C07C103/52; C07G7/00; C08G81/00
Foreign References:
JPS58154596A1983-09-14
JPS5042087A1975-04-16
JPS57192435A1982-11-26
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