COMPOSITION FOR BONE REGENERATION

WIPO Patent Application WO/2010/114319

A3

The present invention relates to a composition for bone regeneration including a hyaluronic acid and a mesenchymal stem cell into which a bone regeneration inducing factor is introduced, and a manufacturing method thereof. The composition for bone regeneration can include a stem cell into which a gene coding a protein with a bone formation function is introduced or cells differentiated from the stem cell and the hyaluronic acid. The protein with the bone formation function can be a bone morphogenic protein (BMP). The stem cell can be a mesenchymal stem cell, and it can be a stem cell into which a suicide gene is additionally introduced. An average molecular weight of the hyaluronic acid can be from 50,000 to 300,000 daltons.

WO/2003/074684	CELLS CAPABLE OF DIFFERENTIATING INTO MYOCARDIUM-LIKE CELLS
WO/2003/013570	PLATELET-DERIVED GROWTH FACTOR PROTECTION OF CARDIAC MYOCARDIUM
WO/2011/056389	METHOD OF MAKING AN ARTIFICIAL MICRO-GLAND USING TAXIS

LIM CHAE-LYUL (KR)
CHOI KYOUNG-BAEK (KR)
LEE HYEON-YOUL (KR)
HYUN JONG-PIL (KR)

PCT/KR2010/001995

March 10, 2011

March 31, 2010

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KOLON LIFE SCIENCE (KR)
LIM CHAE-LYUL (KR)
CHOI KYOUNG-BAEK (KR)
LEE HYEON-YOUL (KR)
HYUN JONG-PIL (KR)

A61K35/12; A61K35/00; A61K35/28; A61P19/00

KR20070113572A	2007-11-29
KR20030015160A	2003-02-20

EGERMANN, M. ET AL.: "The potential of gene therapy for fracture healing in osteoporosis", OSTEOPOROS. INT., vol. 16, 2005, pages S120 - S128
GAFNI, Y. ET AL.: "Stem cells as vehicles for orthopedic gene therapy", GENE THERAPY, vol. 11, 2004, pages 417 - 426

CHEONJEE INTERNATIONAL PATENT & LAW FIRM (1570-1 Seocho 3-dong, Seocho-gu, Seoul 137-874, KR)

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