Title:
COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF LUNG CANCER
Document Type and Number:
WIPO Patent Application WO2002047534
Kind Code:
A3
Abstract:
Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.
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Inventors:
WANG TONGTONG (US)
WANG AIJUN (US)
SKEIKY YASIR A W (US)
LI SAMUEL X (US)
KALOS MICHAEL D (US)
HENDERSON ROBERT A (US)
MCNEILL PATRICIA D (US)
FANGER NEIL (US)
RETTER MARC W (US)
DURHAM MARGARITA (US)
FANGER GARY R (US)
VEDVICK THOMAS S (US)
CARTER DARRICK (US)
WATANABE YOSHIHIRO (US)
PECKHAM DAVID W (US)
CAI FENG (US)
FOY TERESA M (US)
WANG AIJUN (US)
SKEIKY YASIR A W (US)
LI SAMUEL X (US)
KALOS MICHAEL D (US)
HENDERSON ROBERT A (US)
MCNEILL PATRICIA D (US)
FANGER NEIL (US)
RETTER MARC W (US)
DURHAM MARGARITA (US)
FANGER GARY R (US)
VEDVICK THOMAS S (US)
CARTER DARRICK (US)
WATANABE YOSHIHIRO (US)
PECKHAM DAVID W (US)
CAI FENG (US)
FOY TERESA M (US)
Application Number:
PCT/US2001/047576
Publication Date:
August 22, 2002
Filing Date:
November 30, 2001
Export Citation:
Assignee:
CORIXA CORP (US)
WANG TONGTONG (US)
WANG AIJUN (US)
SKEIKY YASIR A W (US)
LI SAMUEL X (US)
KALOS MICHAEL D (US)
HENDERSON ROBERT A (US)
MCNEILL PATRICIA D (US)
FANGER NEIL (US)
RETTER MARC W (US)
DURHAM MARGARITA (US)
FANGER GARY R (US)
VEDVICK THOMAS S (US)
CARTER DARRICK (US)
WATANABE YOSHIHIRO (US)
PECKHAM DAVID W (US)
CAI FENG (US)
FOY TERESA M (US)
WANG TONGTONG (US)
WANG AIJUN (US)
SKEIKY YASIR A W (US)
LI SAMUEL X (US)
KALOS MICHAEL D (US)
HENDERSON ROBERT A (US)
MCNEILL PATRICIA D (US)
FANGER NEIL (US)
RETTER MARC W (US)
DURHAM MARGARITA (US)
FANGER GARY R (US)
VEDVICK THOMAS S (US)
CARTER DARRICK (US)
WATANABE YOSHIHIRO (US)
PECKHAM DAVID W (US)
CAI FENG (US)
FOY TERESA M (US)
International Classes:
G01N33/574; A61K31/7088; A61K35/14; A61K38/00; A61K39/00; A61K39/395; A61K45/00; A61P35/00; A61P37/04; C07K14/47; C07K14/82; C07K16/30; C07K16/32; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/07; C12N5/0783; C12N5/09; C12N5/10; C12N15/09; C12Q1/68; (IPC1-7): C07H21/02; C07H21/04; A01N43/04; C12N15/00; C12N15/63
Foreign References:
| US6297364B1 | 2001-10-02 |
Other References:
DATABASE GENBANK [online] CHEN ET AL.: "Nucleotides representing cancer-associated genes, used to develop products for the diagnosis, monitoring and treatment of cancers", XP002951204, accession no. STN Database accession no. (AAZ36150)
DATABASE GENBANK [online] WANG ET AL.: "Isolated polypeptide comprising and immunogenic portion of a lung tumor protein is used for detecting and monitoring progression of lung cancer in a patient", XP002951203, accession no. STN Database accession no. (AAC66035)
JOLLY, D.: "Viral vector systems for gene therapy", CANCER GENE THERAPY, vol. 1, no. 1, 1994, pages 51 - 64, XP001079812
DATABASE GENBANK [online] WANG ET AL.: "Isolated polypeptide comprising and immunogenic portion of a lung tumor protein is used for detecting and monitoring progression of lung cancer in a patient", XP002951203, accession no. STN Database accession no. (AAC66035)
JOLLY, D.: "Viral vector systems for gene therapy", CANCER GENE THERAPY, vol. 1, no. 1, 1994, pages 51 - 64, XP001079812
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