CRYSTAL FORM A OF 2-(2,5-DIOXOPYRROLIDIN-1YL)ETHYLMETHYLFUMARATE, PREPARATION METHOD THEREFOR AND USE THEREOF

Title:

CRYSTAL FORM A OF 2-(2,5-DIOXOPYRROLIDIN-1YL)ETHYLMETHYLFUMARATE, PREPARATION METHOD THEREFOR AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2020/198940

Kind Code:

A1

Abstract:

Provided is a crystal form A of 2-(2,5-dioxopyrrolidin-1yl)ethylmethylfumarate. The crystal form has a good light irradiation stability, high-temperature stability and high-humidity stability.

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Inventors:

REN GUOBIN (CN)
YI DONGXU (CN)
JI WEIJIE (CN)
HUANG JIAJUN (CN)

Application Number:

PCT/CN2019/080420

Publication Date:

October 08, 2020

Filing Date:

March 29, 2019

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Assignee:

SHENZHEN RENTAI PHARMATECH LTD (CN)

International Classes:

C07C69/60; A61K31/225; A61K31/40; A61P25/00; C07C69/90; C07D207/404

Domestic Patent References:

WO2017108960A1	2017-06-29
WO2016182898A1	2016-11-17

Foreign References:

US20170056372A1	2017-03-02
CN105452213A	2016-03-30
CN107205985A	2017-09-26

Attorney, Agent or Firm:

SUNSHINE INTELLECTUAL PROPERTY INTERNATIONAL CO., LTD. (CN)

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