DIHYDROURACIL COMPOUNDS AS ANTI-ICTOGENIC OR ANTI-EPILEPTOGENIC AGENTS

Title:

DIHYDROURACIL COMPOUNDS AS ANTI-ICTOGENIC OR ANTI-EPILEPTOGENIC AGENTS

Document Type and Number:

WIPO Patent Application WO2004009559

Kind Code:

A3

Abstract:

Methods and compounds useful for the inhibition of convulsive disorders, including epilepsy, are disclosed. The methods and compounds of the invention inhibit or prevent or treat ictogenesis, epileptogenesis, or epileptogenesis-associated conditions. Methods for preparing the compounds of the invention are also described. Particularly preferred compounds of the invention include Formula 1 as described herein.

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Inventors:

JONES KATHRYN A (CA)
WEAVER DONALD F (CA)
TIEDJE KATHRYN E (CA)

Application Number:

PCT/CA2003/001082

Publication Date:

April 01, 2004

Filing Date:

July 18, 2003

Export Citation:

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Assignee:

UNIV KINGSTON (CA)
JONES KATHRYN A (CA)
WEAVER DONALD F (CA)
TIEDJE KATHRYN E (CA)

International Classes:

A61P25/08; C07D239/22; (IPC1-7): A61K31/513; A61P25/08; C07D239/22

Domestic Patent References:

WO2002083651A2

2002-10-24

Foreign References:

US4588729A

1986-05-13

Other References:

DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002261204, retrieved from STN accession no. 1987:107921 Database accession no. 1987:107921

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