Title:
FAMSIN ORCHESTRATES METABOLIC ADAPTATIONS TO FAMINE
Document Type and Number:
WIPO Patent Application WO/2023/000223
Kind Code:
A1
Abstract:
An isolated polypeptide, an isolated nucleic acid, a hyperglycemia marker, use of the detection reagent in the preparation of a kit, use of the first agent in the preparation of a medicine, a pharmaceutical composition, food or health product for improving starvation tolerance, use of the second agent in the preparation of a medicine, a pharmaceutical composition for treating or preventing diabetes, a method for improving starvation tolerance, a method of weight loss, a method for the treatment or prevention of diabetes, a method for screening drugs for improving starvation tolerance and a method for screening drugs for the treatment or prevention of diabetes.
Inventors:
WANG YIGUO (CN)
LONG AIJUN (CN)
LIU YANG (CN)
LONG AIJUN (CN)
LIU YANG (CN)
Application Number:
PCT/CN2021/107690
Publication Date:
January 26, 2023
Filing Date:
July 21, 2021
Export Citation:
Assignee:
UNIV TSINGHUA (CN)
International Classes:
A61K38/17; A61K48/00; A61P3/04; A61P3/08
Domestic Patent References:
| WO2011144517A1 | 2011-11-24 |
Foreign References:
| US20200261392A1 | 2020-08-20 | |||
| US20140377353A1 | 2014-12-25 | |||
| US20150224081A1 | 2015-08-13 | |||
| CN104288782A | 2015-01-21 |
Other References:
BAILEY SWNEKE D., XIE CHANGCHUN, DO RON, MONTPETIT ALEXANDRE, DIAZ RAFAEL, MOHAN VISWANATHAN, KEAVNEY BERNARD, YUSUF SALIM, GERSTE: "Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study", DIABETES CARE, AMERICAN DIABETES ASSOCIATION, ALEXANDRIA, VA, US, vol. 33, no. 10, 1 October 2010 (2010-10-01), US , pages 2250 - 2253, XP093027198, ISSN: 0149-5992, DOI: 10.2337/dc10-0452
DATABASE GenPept Protein ; ANONYMOUS : "chromosome 17 open reading frame 78, isoform CRA_b [Homo sapiens] ", XP093027202, retrieved from NCBI
DATABASE GenPept Protein; ANONYMOUS : "Sequence 60558 from patent US 8586006 ", XP093027207, retrieved from NCBI
GUO ZHANHONG, ZANG PU: "Ghrelin with glucose，lipid metabolism，energy balance and obesity", CHINESE JOURNAL OF DIABETES, vol. 27, no. 4, 1 April 2019 (2019-04-01), pages 316 - 320, XP093027216
DATABASE GenPept Protein ; ANONYMOUS : "chromosome 17 open reading frame 78, isoform CRA_b [Homo sapiens] ", XP093027202, retrieved from NCBI
DATABASE GenPept Protein; ANONYMOUS : "Sequence 60558 from patent US 8586006 ", XP093027207, retrieved from NCBI
GUO ZHANHONG, ZANG PU: "Ghrelin with glucose，lipid metabolism，energy balance and obesity", CHINESE JOURNAL OF DIABETES, vol. 27, no. 4, 1 April 2019 (2019-04-01), pages 316 - 320, XP093027216
Attorney, Agent or Firm:
TSINGYIHUA INTELLECTUAL PROPERTY LLC (CN)
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