Title:
FIBROSIS-INDUCING GENE EXPRESSION INHIBITOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/090967
Kind Code:
A1
Abstract:
Provided is an expression inhibitor capable of inhibiting the expression of a fibrosis-inducing gene. The expression inhibitor according to the present invention comprises a compound represented by formula (I) or a salt thereof.
Inventors:
ENOMOTO HATSUNE (JP)
TACHIKI HIDEHISA (JP)
NAKASHIMA MIKIRO (JP)
OHYAMA KANAME (JP)
SOKI HIROSHI (JP)
MIYAMOTO HIROTAKA (JP)
INAMINE TATSUO (JP)
TERAI SHUJI (JP)
KAMIMURA KENYA (JP)
SAKAI NORIHIRO (JP)
TACHIKI HIDEHISA (JP)
NAKASHIMA MIKIRO (JP)
OHYAMA KANAME (JP)
SOKI HIROSHI (JP)
MIYAMOTO HIROTAKA (JP)
INAMINE TATSUO (JP)
TERAI SHUJI (JP)
KAMIMURA KENYA (JP)
SAKAI NORIHIRO (JP)
Application Number:
PCT/JP2019/042747
Publication Date:
May 07, 2020
Filing Date:
October 31, 2019
Export Citation:
Assignee:
TOWA PHARMACEUTICAL CO LTD (JP)
UNIV NAGASAKI (JP)
UNIV NIIGATA (JP)
UNIV NAGASAKI (JP)
UNIV NIIGATA (JP)
International Classes:
A61K31/4196; A61P1/16; A61P3/06; A61P7/00; A61P9/10; A61P11/00; A61P17/00
Foreign References:
| CN103157110A | 2013-06-19 | |||
| JP2010505783A | 2010-02-25 |
Other References:
BENDERLI, C. Y. ET AL.: "Effects of hormonotherapy administered after concurrent radiotherapy and Trastuzumab on pulmonary fibrosis", HIPPOKRATIA, vol. 17, no. 3, July 2013 (2013-07-01), pages 228 - 232, XP055704330
LO, C. ET AL.: "Stromal response to aromatase inhibition is associated with improved treatment response in breast cancer patients", EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, vol. 36, no. 11, November 2010 (2010-11-01), pages 1099 - 1100, XP027366804
LO, C. ET AL.: "Stromal response to aromatase inhibition is associated with improved treatment response in breast cancer patients", EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, vol. 36, no. 11, November 2010 (2010-11-01), pages 1099 - 1100, XP027366804
Attorney, Agent or Firm:
TSUJIMARU Koichiro et al. (JP)
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