Title:
FUSED PIPERIDINE COMPOUND AND PHARMACEUTICAL AGENT COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO2010110380
Kind Code:
A1
Abstract:
Disclosed is a compound having an activity of promoting the production of a low-molecular-weight EPO and/or an activity of promoting the production of hemoglobin. Specifically disclosed is a fused piperidine compound represented by general formula (1) [wherein ring A represents a C10-14 aryl group, or a 5- to 10-membered heterocyclic group; ring B represents a C6-14 aryl group, or the like; X represents N-R7, a sulfur atom, or an oxygen atom; R1, R2, R2', R3 and R3' independently represent a hydrogen atom, a C1-6 alkyl group, or a C3-6 cycloalkyl group; and R4, R5 and R6 independently represent a hydrogen atom, or a halogen atom], a salt of the fused piperidine compound, or a solvate of the fused piperidine compound or the salt.
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Inventors:
ASHIKAWA MASANORI (JP)
MORIMOTO TOSHIHARU (JP)
YAMADA HAJIME (JP)
TAKEMURA SHUNJI (JP)
NISHIYAMA TATSUAKI (JP)
DOI TAKESHI (JP)
ISHIWATA HIROYUKI (JP)
MORIMOTO TOSHIHARU (JP)
YAMADA HAJIME (JP)
TAKEMURA SHUNJI (JP)
NISHIYAMA TATSUAKI (JP)
DOI TAKESHI (JP)
ISHIWATA HIROYUKI (JP)
Application Number:
PCT/JP2010/055260
Publication Date:
September 30, 2010
Filing Date:
March 25, 2010
Export Citation:
Assignee:
KOWA CO (JP)
ASHIKAWA MASANORI (JP)
MORIMOTO TOSHIHARU (JP)
YAMADA HAJIME (JP)
TAKEMURA SHUNJI (JP)
NISHIYAMA TATSUAKI (JP)
DOI TAKESHI (JP)
ISHIWATA HIROYUKI (JP)
ASHIKAWA MASANORI (JP)
MORIMOTO TOSHIHARU (JP)
YAMADA HAJIME (JP)
TAKEMURA SHUNJI (JP)
NISHIYAMA TATSUAKI (JP)
DOI TAKESHI (JP)
ISHIWATA HIROYUKI (JP)
International Classes:
A61K31/4355; C07D221/06; A61K31/436; A61K31/437; A61K31/4375; A61K31/473; A61K31/4738; A61K31/5383; A61P7/06; A61P43/00; C07D471/04; C07D491/052; C07D491/056; C07D498/04
Domestic Patent References:
| WO2006040318A2 | 2006-04-20 | |||
| WO2004034985A2 | 2004-04-29 | |||
| WO2006094292A2 | 2006-09-08 | |||
| WO2005097806A1 | 2005-10-20 | |||
| WO2009041072A1 | 2009-04-02 |
Foreign References:
| EP0992496A1 | 2000-04-12 |
Other References:
ANGEW. CHEM. INT. ED., vol. 37, 1998, pages 2046
ORG. LETT., vol. 5, 2003, pages 2413
TETRAHEDRON LETT., 2003, pages 1691
See also references of EP 2412710A4
ORG. LETT., vol. 5, 2003, pages 2413
TETRAHEDRON LETT., 2003, pages 1691
See also references of EP 2412710A4
Attorney, Agent or Firm:
AOKI, Atsushi et al. (JP)
Aoki 篤 (JP)
Aoki 篤 (JP)
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