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Patent Searching and Data


Title:
FUSION PROTEIN SUBSTRATE FOR PROTEASE ACTIVITY MEASUREMENT
Document Type and Number:
WIPO Patent Application WO/2022/259904
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a novel protease activity measurement method that can be used in a high-throughput manner and enables activity measurement based on the full-length amino acid sequence of a protease. Provided is a fusion protein substrate for protease activity measurement, said fusion protein substrate containing, in order from the N-terminal side, (i) a signal sequence, a reporter region, a protease target region and a membrane-binding region, or (ii) a signal sequence, a protease target region, a reporter region and a membrane-binding region.

Inventors:
OGAWA KENJI (JP)
Application Number:
PCT/JP2022/022041
Publication Date:
December 15, 2022
Filing Date:
May 31, 2022
Export Citation:
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Assignee:
RIKEN (JP)
International Classes:
C12N15/62; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/50; C12N15/63; C12Q1/37
Foreign References:
JP2002543797A2002-12-24
JP2013512692A2013-04-18
JP2008503219A2008-02-07
Attorney, Agent or Firm:
HIRAKI & ASSOCIATES (JP)
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