Title:
HOMING PEPTIDE MULTIMERS, THEIR PREPARATION AND USES
Document Type and Number:
WIPO Patent Application WO2002043770
Kind Code:
A3
Abstract:
Synthetic multimeric ligands that provide for enhanced cell-, and organ- specific targeting are described and claimed, as are methods of their preparation and use.
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Inventors:
DANISHEFSKY SAMUEL J (US)
FRITZ LAWRENCE C (US)
FRITZ LAWRENCE C (US)
Application Number:
PCT/US2001/044154
Publication Date:
November 06, 2003
Filing Date:
November 26, 2001
Export Citation:
Assignee:
CONFORMA THERAPEUTIC CORP (US)
DANISHEFSKY SAMUEL J (US)
FRITZ LAWRENCE C (US)
DANISHEFSKY SAMUEL J (US)
FRITZ LAWRENCE C (US)
International Classes:
A61K47/48; B65D81/36; (IPC1-7): A61K47/48; A61K41/00
Domestic Patent References:
| WO1997007398A1 | 1997-02-27 | |||
| WO1996020236A1 | 1996-07-04 | |||
| WO2001047960A1 | 2001-07-05 | |||
| WO1999059633A1 | 1999-11-25 | |||
| WO1997015668A2 | 1997-05-01 | |||
| WO1996041813A2 | 1996-12-27 | |||
| WO1996024675A1 | 1996-08-15 | |||
| WO1998006848A1 | 1998-02-19 |
Foreign References:
| US6121236A | 2000-09-19 | |||
| US6458933B1 | 2002-10-01 | |||
| US5011686A | 1991-04-30 |
Other References:
BLACKWELL H E ET AL: "NEW APPROACHES TO OLEFIN CROSS-METATHESIS", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, vol. 122, no. 1, 12 January 2000 (2000-01-12), pages 58 - 71, XP000891075, ISSN: 0002-7863
STILLE J K: "THE PALLADIUM-CATALYZED CROSS-COUPLING REACTIONS OF ORGANOTIN REAGENTS WITH ORGANIC ELECTROPHILES", ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, VERLAG CHEMIE. WEINHEIM, DE, vol. 25, 1986, pages 508 - 524, XP000872970, ISSN: 0570-0833
MIYAURA N ET AL: "PALLADIUM-CATALYZED INTER- AND INTRAMOLECULAR CROSS-COUPLING REACTIONS OF B-ALKYL-9-BORABICYCLOU3.3.1NONANE DERIVATIVES WITH 1-HALO-1-ALKENES OR HALOARENES. SYNTHESES OF FUNCTIONALIZED ALKENES, ARENES, AND CYCLOALKENES VIA A HYDROBORATION-COUPLING SEQUENCE", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, vol. 111, no. 1, 1989, pages 314 - 321, XP000650210, ISSN: 0002-7863
GUO L H ET AL: "DIRECT UN-MEDIATED ELECTROCHEMISTRY OF THE ENZYME P-CRESOLMETHYLHYDROXYLASE", JOURNAL OF ELECTROANALYTICAL CHEMISTRY AND INTERFACIAL ELECTROCHEMISTRY, ELSEVIER, AMSTERDAM, NL, vol. 266, no. 2, 25 July 1989 (1989-07-25), pages 379 - 396, XP002038924, ISSN: 0022-0728
STILLE J K: "THE PALLADIUM-CATALYZED CROSS-COUPLING REACTIONS OF ORGANOTIN REAGENTS WITH ORGANIC ELECTROPHILES", ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, VERLAG CHEMIE. WEINHEIM, DE, vol. 25, 1986, pages 508 - 524, XP000872970, ISSN: 0570-0833
MIYAURA N ET AL: "PALLADIUM-CATALYZED INTER- AND INTRAMOLECULAR CROSS-COUPLING REACTIONS OF B-ALKYL-9-BORABICYCLOU3.3.1NONANE DERIVATIVES WITH 1-HALO-1-ALKENES OR HALOARENES. SYNTHESES OF FUNCTIONALIZED ALKENES, ARENES, AND CYCLOALKENES VIA A HYDROBORATION-COUPLING SEQUENCE", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, vol. 111, no. 1, 1989, pages 314 - 321, XP000650210, ISSN: 0002-7863
GUO L H ET AL: "DIRECT UN-MEDIATED ELECTROCHEMISTRY OF THE ENZYME P-CRESOLMETHYLHYDROXYLASE", JOURNAL OF ELECTROANALYTICAL CHEMISTRY AND INTERFACIAL ELECTROCHEMISTRY, ELSEVIER, AMSTERDAM, NL, vol. 266, no. 2, 25 July 1989 (1989-07-25), pages 379 - 396, XP002038924, ISSN: 0022-0728
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