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Title:
AN IMPROVED PROCESS FOR THE PREPARATION OF PENTOSAN POLYSULFATE OR SALTS THEREOF
Document Type and Number:
WIPO Patent Application WO/2012/101544
Kind Code:
A1
Abstract:
The present invention relates to an improved process for the preparation of Pentosan polysulfate of formula (I) or salt thereof, wherein R represents -SO3Y, and Y is at least one member selected from the group consisting of H and a pharmaceutically acceptable cation such as sodium, potassium, and magnesium which provides in particular to a narrow distribution low molecular weight, highly sulfated Pentosan polysulfate (in this instance a Xylan).

Inventors:
RAMAN JAYARAMAN VENKAT (IN)
PILLAI BIJUKUMAR GOPINATHAN (IN)
BALAJI SUNDARA KALYANA (IN)
PATEL HITESH (IN)
DHAMELIYA DHARMESH (IN)
JINJALA GOVIND (IN)
Application Number:
PCT/IB2012/050213
Publication Date:
August 02, 2012
Filing Date:
January 17, 2012
Export Citation:
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Assignee:
ALEMBIC PHARMACEUTICALS LTD (IN)
RAMAN JAYARAMAN VENKAT (IN)
PILLAI BIJUKUMAR GOPINATHAN (IN)
BALAJI SUNDARA KALYANA (IN)
PATEL HITESH (IN)
DHAMELIYA DHARMESH (IN)
JINJALA GOVIND (IN)
International Classes:
C08B37/14
Domestic Patent References:
WO2010000013A12010-01-07
WO2008107906A12008-09-12
Foreign References:
US4699900A1987-10-13
US2689848A1954-09-21
US4713373A1987-12-15
Other References:
OFOSU F A ET AL: "2 Mechanisms of action of low molecular weight heparins and heparinoids", BAILLIERE'S CLINICAL HAEMATOLOGY, BAILLIERE TINDALL, LONDON, GB, vol. 3, no. 3, 1 July 1990 (1990-07-01), pages 505 - 529, XP026166376, ISSN: 0950-3536, [retrieved on 19900701], DOI: 10.1016/S0950-3536(05)80016-2
Attorney, Agent or Firm:
PATHAK, Alpesh (Patent CellAlembic Road, Gujarat, Vadodara 3, IN)
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Claims: