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Title:
LIPID PARTICLE CONTAINING A-TYPE CpG OLIGODEOXYNUCLEOTIDE
Document Type and Number:
WIPO Patent Application WO/2020/017590
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a technology that can stably express the effect of an A-type CpG oligodeoxynucleotide. Said problem is solved by a lipid particle containing an A-type CpG oligodeoxynucleotide.

Inventors:
AOSHI TAIKI (JP)
KOYAMA SHOHEI (JP)
SUZUKI RYO (JP)
Application Number:
PCT/JP2019/028269
Publication Date:
January 23, 2020
Filing Date:
July 18, 2019
Export Citation:
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Assignee:
THE RESEARCH FOUNDATION FOR MICROBIAL DISEASES 0F OSAKA UNIV (JP)
UNIV OSAKA (JP)
UNIV TEIKYO (JP)
International Classes:
A61K31/7088; A61K9/127; A61K9/133; A61K47/18; A61K48/00; A61P35/00; A61P37/04
Domestic Patent References:
WO2005014110A12005-02-17
WO2017193081A12017-11-09
WO2016103703A12016-06-30
WO2003040308A22003-05-15
WO2016103703A12016-06-30
Foreign References:
JP2003510290A2003-03-18
JP2008148556A2008-07-03
Other References:
PIETER R CULLIS; MICHAEL J HOPE: "Lipid Nanoparticle Systems for Enabling Gene Therapies", MOLECULAR THERAPY, vol. 25, no. 7, 1 July 2017 (2017-07-01), pages 1467 - 1475, XP055548712, ISSN: 1525-0016, DOI: 10.1016/j.ymthe.2017.03.013
TANIMOTO, YOSHIHIKO; MUNAKATA RISA; OSA AKIO; TSUTOMU KIYOSHI; HASEDA YASUNARI; YOSHIOKA YASUO; OKADA YOSHIAKI; KOYAMA SHOHEI; SUZ: "Anti-tumor effects of D35 and lipid complexes", PROGRAM AND ABSTRACT OF THE 22ND ANNUAL MEETING OF THE JAPANESE SOCIETY FOR VACCINOLOGY; DECEMBER 8-9, 2018, vol. 22nd, 20 November 2018 (2018-11-20), pages 89, XP009525473
KAWAMOTO, MEGUMI : "Development of lipid nanoparticles loaded with immunostimulatory nucleic acids and their effectiveness and safety evaluation", ABSTRACTS OF THE 62ND CONFERENCE OF THE PHARMACEUTICAL SOCIETY OF JAPAN KANTO BRANCH AND THE YOUNG MEMBERS SYMPOSIUM OF THE PHARMACEUTICAL SOCIETY OF JAPAN KANTO BRANCH; SEPTEMBER 15, 2018, vol. 62, 10 September 2018 (2018-09-10), pages 1 - 3, XP009525474
See also references of EP 3824891A4
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
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