LIPOSOME COMPOSITION AND LIPOSOME-CONTAINING PHARMACEUTICAL COMPOSITION

Title:

LIPOSOME COMPOSITION AND LIPOSOME-CONTAINING PHARMACEUTICAL COMPOSITION

Document Type and Number:

WIPO Patent Application WO/2023/190709

Kind Code:

A1

Abstract:

A liposome composition which comprises (A) liposomes containing dihydrosphingomyelin and a diacylglycerol-polyethylene glycol, (B) a drug and (C) a sulfate and/or sucrose octasulfate, and in which (A) encapsulates (B), wherein: the diacylglycerol-polyethylene glycol is distearoylglycerol-polyethylene glycol; and (B) is 4-(3-chloro-4-(ethylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide represented by formula (I) or pharmaceutically acceptable salt thereof.

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Inventors:

MATSUMOTO YASUNOBU (JP)
HYODO KENJI (JP)
TAKASE YASUTAKA (JP)
KATSURADA YURI (JP)
ANDO YUICHIRO (JP)
ONIZAWA YUJI (JP)
SUZUKI TAKUYA (JP)

Application Number:

PCT/JP2023/012862

Publication Date:

October 05, 2023

Filing Date:

March 29, 2023

Export Citation:

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Assignee:

EISAI R&D MAN CO LTD (JP)

International Classes:

A61K9/127; A61K31/47; A61K47/02; A61K47/12; A61K47/14; A61K47/24; A61K47/26; A61K47/28; A61P35/00; C07D215/48

Domestic Patent References:

WO2012144463A1	2012-10-26
WO2006030941A1	2006-03-23
WO2021226368A1	2021-11-11
WO2018181963A1	2018-10-04

Foreign References:

CN112603890A

2021-04-06

Attorney, Agent or Firm:

HASEGAWA Yoshiki et al. (JP)

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