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Title:
MASP-2-TARGETTING ANTIBODIES AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/174039
Kind Code:
A1
Abstract:
Disclosed herein are anti-MASP-2 antibodies and antigen-binding fragments, polynucleotides encoding the antibodies and antigen-binding fragments, and pharmaceutical compositions comprising the antibodies and antigen-binding fragments. Uses of the anti-MASP-2 antibodies and antigen-binding fragments described herein in treatment of conditions and disorders associated completement activation are also disclosed.

Inventors:
GUO CHONGTIAN (CN)
LEI RUN (CN)
FAN PENGCHENG (CN)
FAN LIHUA (CN)
XU ZHIHAO (CN)
SUN QIANG (CN)
WANG JONATHAN JIAN (CN)
Application Number:
PCT/CN2023/078260
Publication Date:
September 21, 2023
Filing Date:
February 24, 2023
Export Citation:
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Assignee:
INMAGENE BIOPHARMACEUTICALS HANGZHOU CO LTD (CN)
INMAGENE PTE LTD (SG)
International Classes:
C07K16/40; A61K39/395; A61P1/00; A61P3/00; A61P5/00; A61P7/00; A61P9/00; A61P11/00; A61P13/00; A61P15/00; A61P17/00; A61P19/00; A61P21/00; A61P25/00; C12N15/13; C12N15/63
Domestic Patent References:
WO2021178902A12021-09-10
Foreign References:
CN102781471A2012-11-14
CN1449440A2003-10-15
CN103687620A2014-03-26
CN1798769A2006-07-05
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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