Title:
METHOD FOR PRODUCING AROMATIC COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/2023/106352
Kind Code:
A1
Abstract:
Provided is a method for efficiently producing aromatic compounds by using transformed cells. This method for producing an aromatic compound or a salt thereof comprises a step for culturing a transformed cell in which the function of the monocarboxylate transporter indicated by (A) or (B) has been suppressed or deleted. (A) polypeptide comprising the amino acid sequence given by SEQ ID NO: 2; (B) polypeptide having a monocarboxylate transporter activity and comprising an amino acid sequence having at least 90% identity with the amino acid sequence given by SEQ ID NO: 2
Inventors:
KANEDA JITSURO (JP)
TAKAHASHI FUMIKAZU (JP)
TAKAHASHI FUMIKAZU (JP)
Application Number:
PCT/JP2022/045190
Publication Date:
June 15, 2023
Filing Date:
December 07, 2022
Export Citation:
Assignee:
KAO CORP (JP)
International Classes:
C12P7/22; C12N1/21; C12N15/31
Domestic Patent References:
| WO2021241508A1 | 2021-12-02 |
Other References:
WANG YU, FAN LIWEN, TUYISHIME PHILIBERT, LIU JIAO, ZHANG KUN, GAO NING, ZHANG ZHIHUI, NI XIAOMENG, FENG JINHUI, YUAN QIANQIAN, MA : "Adaptive laboratory evolution enhances methanol tolerance and conversion in engineered Corynebacterium glutamicum", COMMUNICATIONS BIOLOGY, vol. 3, no. 1, XP093070008, DOI: 10.1038/s42003-020-0954-9
ELENA JOLKVER, DENISE EMER, STEFAN BALLAN, REINHARD KRÄMER, BERNHARD J. EIKMANNS, KAY MARIN: "Identification and Characterization of a Bacterial Transport System for the Uptake of Pyruvate, Propionate, and Acetate in Corynebacterium glutamicum", JOURNAL OF BACTERIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 191, no. 3, 1 February 2009 (2009-02-01), US , pages 940 - 948, XP055314571, ISSN: 0021-9193, DOI: 10.1128/JB.01155-08
KAPPELMANN JANNICK, KLEIN BIANCA, PAPENFUSS MATHIAS, LANGE JULIAN, BLOMBACH BASTIAN, TAKORS RALF, WIECHERT WOLFGANG, POLEN TINO, N: "Comprehensive Analysis of C. glutamicum Anaplerotic Deletion Mutants Under Defined d-Glucose Conditions", FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, vol. 8, XP093070012, DOI: 10.3389/fbioe.2020.602936
ELENA JOLKVER, DENISE EMER, STEFAN BALLAN, REINHARD KRÄMER, BERNHARD J. EIKMANNS, KAY MARIN: "Identification and Characterization of a Bacterial Transport System for the Uptake of Pyruvate, Propionate, and Acetate in Corynebacterium glutamicum", JOURNAL OF BACTERIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 191, no. 3, 1 February 2009 (2009-02-01), US , pages 940 - 948, XP055314571, ISSN: 0021-9193, DOI: 10.1128/JB.01155-08
KAPPELMANN JANNICK, KLEIN BIANCA, PAPENFUSS MATHIAS, LANGE JULIAN, BLOMBACH BASTIAN, TAKORS RALF, WIECHERT WOLFGANG, POLEN TINO, N: "Comprehensive Analysis of C. glutamicum Anaplerotic Deletion Mutants Under Defined d-Glucose Conditions", FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, vol. 8, XP093070012, DOI: 10.3389/fbioe.2020.602936
Attorney, Agent or Firm:
ARUGA PATENT OFFICE (JP)
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