Title:
METHOD OF PURIFYING MACROLIDES
Document Type and Number:
WIPO Patent Application WO2005010015
Kind Code:
B1
Abstract:
Provided is a method of purifying a macrolide, especially tacrolimus, that includes loading macrolide onto a bed of sorption resin and elting with a suitable eluent such as a combination of water and tetrahydrofuran.
Inventors:
KERI VILMOS (HU)
CZOVEK ZOLTAN (HU)
CSORVASI ANDREA (HU)
RANTAL FERENC (HU)
CZOVEK ZOLTAN (HU)
CSORVASI ANDREA (HU)
RANTAL FERENC (HU)
Application Number:
PCT/US2004/024318
Publication Date:
March 17, 2005
Filing Date:
July 26, 2004
Export Citation:
Assignee:
TEVA GYOGYSZERGYAR RESZVENYTAR (HU)
TEVA PHARMA (US)
KERI VILMOS (HU)
CZOVEK ZOLTAN (HU)
CSORVASI ANDREA (HU)
RANTAL FERENC (HU)
TEVA PHARMA (US)
KERI VILMOS (HU)
CZOVEK ZOLTAN (HU)
CSORVASI ANDREA (HU)
RANTAL FERENC (HU)
International Classes:
C07D498/18; (IPC1-7): C07G3/00; C07G5/00; C07D498/18
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