Title:
METHOD FOR REGULATING GROWTH OF DECAPODA CRUSTACEANS
Document Type and Number:
WIPO Patent Application WO/2022/092170
Kind Code:
A1
Abstract:
The present invention provides a means for regulating (accelerating or suppressing) growth of Decapoda crustaceans such as shrimp and crab. The method according to the present invention is for regulating growth of animals belonging to the order Decapoda and comprises a step for regulating (inhibiting or enhancing) functions of genes including at least one growth regulation-related gene selected from the group consisting of those involved in the mTOR pathway and the Akt pathway, and upstream and downstream factors thereof, and optionally further including at least one ecdysis-related gene selected from ecdysis-related factors, or functions of transcription products or translation products of said genes.
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Inventors:
SHINJI JUNPEI (JP)
YONEKITA TARO (JP)
YONEKITA TARO (JP)
Application Number:
PCT/JP2021/039717
Publication Date:
May 05, 2022
Filing Date:
October 27, 2021
Export Citation:
Assignee:
UNIV TOKYO (JP)
NH FOODS LTD (JP)
NH FOODS LTD (JP)
International Classes:
C12N15/113; A01K67/027; C12N15/09
Domestic Patent References:
| WO2018084077A1 | 2018-05-11 |
Foreign References:
| JP2009297021A | 2009-12-24 |
Other References:
FANG HAN, LIU XINWEI, SHAO XUQING, XIN FANG, WANG BAOJIE, WANG MENGQIANG, JIANG KEYONG, LIU MEI, WANG LEI: "Molecular and functional characterization of Raptor in mTOR pathway from Litopenaeus vannamei", AQUACULUTRE RESERCH, BLACKWELL SCIENCE, OXFORD,, GB, vol. 51, no. 6, 1 June 2020 (2020-06-01), GB , pages 2179 - 2189, XP055926766, ISSN: 1355-557X, DOI: 10.1111/are.14522
MYKLES DONALD L., CHANG ERNEST S.: "Hormonal control of the crustacean molting gland: Insights from transcriptomics and proteomics", GENERAL AND COMPARATIVE ENDOCRINOLOGY, ACADEMIC PRESS., US, vol. 294, 1 August 2020 (2020-08-01), US , pages 113493, XP055926768, ISSN: 0016-6480, DOI: 10.1016/j.ygcen.2020.113493
K. S. MACLEA, ABUHAGR A. M., PITTS N. L., COVI J. A., BADER B. D., CHANG E. S., MYKLES D. L.: "Rheb, an activator of target of rapamycin, in the blackback land crab, Gecarcinus lateralis: cloning and effects of molting and unweighting on expression in skeletal muscle", JOURNAL OF EXPERIMENTAL BIOLOGY, COMPANY OF BIOLOGISTS CAMBRIDGE, vol. 215, no. 4, 25 January 2012 (2012-01-25), pages 590 - 604, XP055694673, ISSN: 0022-0949, DOI: 10.1242/jeb.062869
ABUHAGR ALI M., MACLEA KYLE S., CHANG ERNEST S., MYKLES DONALD L.: "Mechanistic target of rapamycin (mTOR) signaling genes in decapod crustaceans: Cloning and tissue expression of mTOR, Akt, Rheb, and p70 S6 kinase in the green crab, Carcinus maenas, and blackback land crab, Gecarcinus lateralis", COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. PART A, MOLECULAR AND INTEGRATIVE PHYSIOLOGY, ELSEVIER SCIENCE, NEW YORK, NY, US, vol. 168, 1 February 2014 (2014-02-01), US , pages 25 - 39, XP055926775, ISSN: 1095-6433, DOI: 10.1016/j.cbpa.2013.11.008
MYKLES DONALD L., CHANG ERNEST S.: "Hormonal control of the crustacean molting gland: Insights from transcriptomics and proteomics", GENERAL AND COMPARATIVE ENDOCRINOLOGY, ACADEMIC PRESS., US, vol. 294, 1 August 2020 (2020-08-01), US , pages 113493, XP055926768, ISSN: 0016-6480, DOI: 10.1016/j.ygcen.2020.113493
K. S. MACLEA, ABUHAGR A. M., PITTS N. L., COVI J. A., BADER B. D., CHANG E. S., MYKLES D. L.: "Rheb, an activator of target of rapamycin, in the blackback land crab, Gecarcinus lateralis: cloning and effects of molting and unweighting on expression in skeletal muscle", JOURNAL OF EXPERIMENTAL BIOLOGY, COMPANY OF BIOLOGISTS CAMBRIDGE, vol. 215, no. 4, 25 January 2012 (2012-01-25), pages 590 - 604, XP055694673, ISSN: 0022-0949, DOI: 10.1242/jeb.062869
ABUHAGR ALI M., MACLEA KYLE S., CHANG ERNEST S., MYKLES DONALD L.: "Mechanistic target of rapamycin (mTOR) signaling genes in decapod crustaceans: Cloning and tissue expression of mTOR, Akt, Rheb, and p70 S6 kinase in the green crab, Carcinus maenas, and blackback land crab, Gecarcinus lateralis", COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. PART A, MOLECULAR AND INTEGRATIVE PHYSIOLOGY, ELSEVIER SCIENCE, NEW YORK, NY, US, vol. 168, 1 February 2014 (2014-02-01), US , pages 25 - 39, XP055926775, ISSN: 1095-6433, DOI: 10.1016/j.cbpa.2013.11.008
Attorney, Agent or Firm:
UMEDA Shinsuke et al. (JP)
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