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Title:
METHOD FOR TREATING PATIENT HAVING UNDERGONE PRE-TRANSPLANTATION PROCESS INVOLVED IN HEMATOPOIETIC STEM CELL TRANSPLANTATION, AND COMPOSITION FOR USE IN SAID METHOD
Document Type and Number:
WIPO Patent Application WO/2023/176709
Kind Code:
A1
Abstract:
The present disclosure provides: a method for treating a patient who has undergone a pre-transplantation process involved in hematopoietic stem cell transplantation; and a composition for use in said method. The composition according to the present disclosure contains bone-marrow common progenitor cells.

Inventors:
YAMAZAKI SATOSHI (JP)
BECKERHANS JIRO (JP)
YOGO TAKAO (JP)
Application Number:
PCT/JP2023/009223
Publication Date:
September 21, 2023
Filing Date:
March 10, 2023
Export Citation:
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Assignee:
UNIV TSUKUBA (JP)
International Classes:
A61K35/28; A61P7/00; C12N5/0775; C12N5/10; C12N15/09
Domestic Patent References:
WO2021049617A12021-03-18
WO2021149799A12021-07-29
Foreign References:
US20110052550A12011-03-03
US20020086422A12002-07-04
Other References:
OCHI KIYOSUMI, MORITA MAIKO, WILKINSON ADAM C., IWAMA ATSUSHI, YAMAZAKI SATOSHI: "Non-conditioned bone marrow chimeric mouse generation using culture-based enrichment of hematopoietic stem and progenitor cells", NATURE COMMUNICATIONS, vol. 12, no. 1, XP093092321, DOI: 10.1038/s41467-021-23763-z
AKASHI K,ET AL: "A clonogenic common myeloid progenitor that gives rise to all myeloid lineages.", CLEO: APPLICATIONS AND TECHNOLOGY 2019 SAN JOSE, CALIFORNIA UNITED STATES 5–10 MAY 2019, OPTICA, vol. 404, no. 6774, 9 March 2000 (2000-03-09), pages 193 - 197, XP002239809, DOI: 10.1038/35004599
Attorney, Agent or Firm:
MORITA Yutaka (JP)
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