Title:
METHODS FOR PREPARING TUMOR-INFILTRATING LYMPHOCYTES
Document Type and Number:
WIPO Patent Application WO/2022/143785
Kind Code:
A1
Abstract:
Provided are methods for expanding tumor-infiltrating lymphocytes (TILs), which include co-culturing an initial cell population containing TILs with first feeder cells to obtain a first expanded cell population; and then co-culturing the first expanded cell population with second feeder cells to obtain an expanded TIL population. The methods can quickly produce a large number of TILs from a small tumor sample.
Inventors:
LI JIA (CN)
HOU JIYAN (CN)
GONG ZIZHEN (CN)
QU YIJIE (CN)
QIN SHICHAO (CN)
WANG SHENCHEN (CN)
SHU WANGQIN (CN)
WU JUNFENG (CN)
WANG FEI (CN)
ZHANG LI (CN)
HOU JIYAN (CN)
GONG ZIZHEN (CN)
QU YIJIE (CN)
QIN SHICHAO (CN)
WANG SHENCHEN (CN)
SHU WANGQIN (CN)
WU JUNFENG (CN)
WANG FEI (CN)
ZHANG LI (CN)
Application Number:
PCT/CN2021/142540
Publication Date:
July 07, 2022
Filing Date:
December 29, 2021
Export Citation:
Assignee:
SHANGHAI CELLULAR BIOPHARMACEUTICAL GROUP LTD (CN)
WUXI CELLULAR BIOPHARMACEUTICAL GROUP LTD (CN)
WUXI CELLULAR BIOPHARMACEUTICAL GROUP LTD (CN)
International Classes:
C12N5/0783
Domestic Patent References:
| WO2020096988A2 | 2020-05-14 | |||
| WO2018204761A1 | 2018-11-08 | |||
| WO2019190579A1 | 2019-10-03 |
Foreign References:
| CN110042080A | 2019-07-23 | |||
| CN111286486A | 2020-06-16 | |||
| CN110199016A | 2019-09-03 | |||
| CN111801415A | 2020-10-20 | |||
| CN110785486A | 2020-02-11 | |||
| CN111040995A | 2020-04-21 | |||
| CN103396991A | 2013-11-20 |
Attorney, Agent or Firm:
ZHONGZI LAW OFFICE (CN)
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