Title:
MICROBIAL MEDIUM COMPOSITION FOR PRODUCING RETINOL, COMPRISING ANTI-OXIDANT, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/182581
Kind Code:
A1
Abstract:
The present application relates to: a method for producing retinol, comprising a step of culturing a Yarrowia sp. microorganism in a medium comprising an anti-oxidant; a method for increasing the production of retinol; a method for producing a retinoid; a Yarrowia sp. microbial medium composition for producing retinol, comprising an anti-oxidant; and a composition for producing retinol, comprising the microorganism or a culture product thereof and an anti-oxidant.
Inventors:
PARK HYE MIN (KR)
LEE PETER (KR)
LEE DONG PIL (KR)
KIM JAE EUNG (KR)
LEE PETER (KR)
LEE DONG PIL (KR)
KIM JAE EUNG (KR)
Application Number:
PCT/KR2022/011046
Publication Date:
September 28, 2023
Filing Date:
July 27, 2022
Export Citation:
Assignee:
CJ CHEILJEDANG CORP (KR)
International Classes:
C12P23/00; C12N1/16; C12N1/38; C12N15/81; C12R1/645
Domestic Patent References:
| WO2019057998A1 | 2019-03-28 |
Foreign References:
| KR20200066752A | 2020-06-11 | |||
| KR20140147982A | 2014-12-31 |
Other References:
HU QIONGYUE, ZHANG TANGLEI, YU HONGWEI, YE LIDAN: "Selective biosynthesis of retinol in S. cerevisiae", BIORESOURCES AND BIOPROCESSING, vol. 9, no. 22, 12 March 2022 (2022-03-12), pages 1 - 14, XP009549063, ISSN: 2197-4365, DOI: 10.1186/s40643-022-00512-8
PARK HYEMIN, LEE DONGPIL, KIM JAE-EUNG, PARK SEONMI, PARK JOO HYUN, HA CHEOL WOONG, BAEK MINJI, YOON SEOK-HWAN, PARK KWANG HYUN, L: "Efficient production of retinol in Yarrowia lipolytica by increasing stability using antioxidant and detergent extraction", METABOLIC ENGINEERING, pages 26 - 37, XP055937136, [retrieved on 20220630], DOI: 10.1016/j.ymben.2022.06.001
PARK HYEMIN, LEE DONGPIL, KIM JAE-EUNG, PARK SEONMI, PARK JOO HYUN, HA CHEOL WOONG, BAEK MINJI, YOON SEOK-HWAN, PARK KWANG HYUN, L: "Efficient production of retinol in Yarrowia lipolytica by increasing stability using antioxidant and detergent extraction", METABOLIC ENGINEERING, pages 26 - 37, XP055937136, [retrieved on 20220630], DOI: 10.1016/j.ymben.2022.06.001
Attorney, Agent or Firm:
HANOL INTELLECTUAL PROPERTY AND LAW (KR)
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