NOVEL FUSED IMIDAZOLE DERIVATIVE

WIPO Patent Application WO/2003/104229

A1

A compound represented by the general formula (I) [wherein T¹ means an optionally substituted, monocyclic or bicyclic, 4- to 12-membered, heterocyclic group containing one or two nitrogen atoms in the ring; X means optionally substituted C_1-6 alkyl, etc.; Z¹ and Z² each independently means nitrogen or a group represented by the formula -CR²-; and R¹ and R² each independently means hydrogen, optionally substituted C_1-6 alkyl, optionally substituted C_1-6 alkoxy, etc.], a salt of the compound, or a hydrate of either. These are novel compounds having excellent DPPIV inhibitory activity.

JP3197963	PIPERAZINYL-AND PIPERIDINYL-CYCLOHEXANOL COMPOUNDS
JPS58140088	NOVEL PYRIMIDINE DERIVATIVE AND ITS PREPARATION
JP2024505250	GPCR receptor agonists, pharmaceutical compositions containing the same, and methods of using them

YOSHIKAWA SEIJI (JP)
EMORI EITA (JP)
MATSUURA FUMIYOSHI (JP)
RICHARD CLARK (JP)
IKUTA HIRONORI (JP)
KIRA KAZUNOBU (JP)
YASUDA NOBUYUKI (JP)
NAGAKURA TADASHI (JP)
YAMAZAKI KAZUTO (JP)

PCT/JP2003/007010

December 18, 2003

June 03, 2003

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EISAI CO LTD (JP)
YOSHIKAWA SEIJI (JP)
EMORI EITA (JP)
MATSUURA FUMIYOSHI (JP)
RICHARD CLARK (JP)
IKUTA HIRONORI (JP)
KIRA KAZUNOBU (JP)
YASUDA NOBUYUKI (JP)
NAGAKURA TADASHI (JP)
YAMAZAKI KAZUTO (JP)

A61K31/496; A61K31/5025; A61K31/522; A61K31/5377; A61K31/541; A61P1/00; A61P3/04; A61P3/06; A61P3/10; A61P9/00; A61P15/00; A61P15/08; A61P19/02; A61P19/10; A61P29/00; A61P31/18; A61P35/00; A61P37/00; A61P37/02; A61P37/08; A61P43/00; C07D473/04; C07D473/06; C07D471/04; C07D473/18; C07D473/22; C07D473/24; C07D473/30; C07D473/36; C07D473/40; C07D487/04; C07D491/14; (IPC1-7): C07D471/04; C07D473/06; C07D473/18; C07D473/22; C07D473/30; C07D473/40; C07D487/04; C07D498/14; A61K31/5025; A61K31/522; A61K31/5365; A61K31/519; A61P1/00; A61P3/04; A61P3/06; A61P3/10; A61P15/00; A61P19/10; A61P29/00; A61P35/00; A61P37/02; A61P37/08; A61P43/00

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WO2000056296A2	2000-09-28
WO2002002560A2	2002-01-10
WO2003004496A1	2003-01-16

EP0206415A2	1986-12-30
US20020161001A1	2002-10-31
US20020198205A1	2002-12-26

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See also references of EP 1514552A4

Shimizu, Hatsushi (1-1-1 Oroshi-mach, Tsuchiura-shi Ibaraki, JP)

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