Title:
PHARMACEUTICAL COMPOSITION CONTAINING PORTULACA GRANDIFLORA HOOK. EXTRACT OR FRACTION THEREOF AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING NEUROINFLAMMATION OR NEURO-DEGENERATIVE DISEASES
Document Type and Number:
WIPO Patent Application WO/2016/032250
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition and a food composition containing Portulaca grandiflora Hook. extract or a fraction thereof as an active ingredient for preventing, treating or ameliorating neuroinflammation or neuro-degenerative diseases. The Portulaca grandiflora Hook. extract or a fraction thereof according to the present invention is derived from a natural product which has been in use as a natural medicinal ingredient, and as such, has no side effects and inhibits expression of NO, PGE2, iNOS and/or COX-2 genes or protein, which are factors associated with inflammation, and is additionally superbly effective for increasing and improving memory and the ability to learn, and thus can be beneficially used to prevent or treat neuroinflammation or neuro-degenerative diseases.
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Inventors:
JANG CHOON GON (KR)
KWON SEUNG HWAN (KR)
CHOI SANG HO (KR)
LEE JOONG KU (KR)
KWON SEUNG HWAN (KR)
CHOI SANG HO (KR)
LEE JOONG KU (KR)
Application Number:
PCT/KR2015/008977
Publication Date:
March 03, 2016
Filing Date:
August 27, 2015
Export Citation:
Assignee:
RES BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY (KR)
International Classes:
A61K36/185; A61P25/16; A61P25/28
Foreign References:
| KR20120117128A | 2012-10-24 | |||
| KR20070065951A | 2007-06-27 | |||
| CN1742866A | 2006-03-08 |
Other References:
ANGHEL, A. I. ET AL.: "Preliminary research on Portulaca grandiflora Hook, species (Portulacaceae) for therapeutic use", FARMACIA, vol. 61, no. 4, 2013, pages 694 - 702, XP055410830
CHAN, K. ET AL.: "The analgesic and anti-inflammatory effects of Portulaca oleracea L. subsp. sativa (Haw.) Celak", JOURNAL OF ETHNOPHARMACOLOGY, vol. 73, no. 3, 2000, pages 445 - 451, XP055410835
See also references of EP 3189846A4
CHAN, K. ET AL.: "The analgesic and anti-inflammatory effects of Portulaca oleracea L. subsp. sativa (Haw.) Celak", JOURNAL OF ETHNOPHARMACOLOGY, vol. 73, no. 3, 2000, pages 445 - 451, XP055410835
See also references of EP 3189846A4
Attorney, Agent or Firm:
SON, MIN (KR)
손민 (KR)
손민 (KR)
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