Title:
PREPARATION METHOD FOR VEGETARIAN D-GLUCOSAMINE HYDROCHLORIDE
Document Type and Number:
WIPO Patent Application WO/2022/174520
Kind Code:
A1
Abstract:
Disclosed is a preparation method for vegetarian D-glucosamine hydrochloride. In the present method, citric acid residual waste obtained after producing citric acid using a fermentation method is used as a raw material, expansion is performed using a gas, and hydrogen chloride is used as a degradation agent, and upon undergoing gas pressure expansion, hydrogen chloride degradation, separation, water washing, decoloration, concentration, filtration, drying, etc. steps, vegetarian D-glucosamine hydrochloride is ultimately obtained. The present invention amply utilizes residual waste from producing citric acid, prepares vegetarian D-glucosamine hydrochloride at a high yield, a product is free of allergens coming from crab and shrimp, and is free of a genetic impurity problem from e. coli fermentation. Product purity reaches 99% and above. The present preparation method has advantages of an abundance of a used raw material, unlimited production resources, low production costs, high product quality, stable product quality, further saving on expenses for environmental stewardship, and having good societal and economic benefits.
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Inventors:
CHEN YANJING (CN)
ZHAN JINMING (CN)
WANG SONGYE (CN)
ZHAN JINMING (CN)
WANG SONGYE (CN)
Application Number:
PCT/CN2021/092125
Publication Date:
August 25, 2022
Filing Date:
May 07, 2021
Export Citation:
Assignee:
JIANGSU AOXIN BIOTECHNOLOGY CO LTD (CN)
International Classes:
C07H5/06; C07H1/00; C07H1/06
Foreign References:
CN112851724A | 2021-05-28 | |||
CN103360432A | 2013-10-23 | |||
CN101429221A | 2009-05-13 | |||
CN101628921A | 2010-01-20 |
Other References:
DING YABO, WANG ZHIWEI, LIU JIE, ZHANG HUAFENG, FENG CHENJUAN, CAO YUNFENG: "Production process for Preparing high-purity D-glucosamine Hydrochloride from citric acid fermentation Residues", JOURNAL OF NORTH PHARMACY, CN, vol. 10, no. 3, 1 March 2013 (2013-03-01), CN , pages 41 - 42, XP055959733, ISSN: 1672-8351
Attorney, Agent or Firm:
LIANYUNGANG RUNZHI PATENT AGENT OFFICE (CN)
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