PROCESS FOR THE PREPARATION OF 3,7-DISUBSTITUTED-2,3,4,5- TETRAHYDRO-1H-1,4-BENZODIAZEPINE COMPOUNDS

Title:

PROCESS FOR THE PREPARATION OF 3,7-DISUBSTITUTED-2,3,4,5- TETRAHYDRO-1H-1,4-BENZODIAZEPINE COMPOUNDS

Document Type and Number:

WIPO Patent Application WO2003041658

Kind Code:

A3

Abstract:

Methods for the synthesis of benzodiazepine compounds having farnesyl protein transferase inhibitory activity.

Inventors:

KRONENTHAL DAVID R (US)
BHANDARU RAO S (US)
SHI ZHONGPING (US)
MUDRYK BOGUSLAW M (US)

Application Number:

PCT/US2002/036818

Publication Date:

January 15, 2004

Filing Date:

November 12, 2002

Export Citation:

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Assignee:

BRISTOL MYERS SQUIBB CO (US)
KRONENTHAL DAVID R (US)
BHANDARU RAO S (US)
SHI ZHONGPING (US)
MUDRYK BOGUSLAW M (US)

International Classes:

A61P35/00; C07C255/58; C07C255/61; C07D233/54; C07D233/66; C07D233/88; C07D233/90; C07D243/14; C07D333/34; C07D403/06; C07D409/12; C07D409/14; C07F7/18; (IPC1-7): A61K31/55; A61P35/00; C07D233/66; C07D233/90; C07D243/14; C07D333/32; C07D333/34; C07C255/00; C07F7/04; C07F7/10

Foreign References:

US6011029A

2000-01-04

Other References: