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Title:
RELAXIN AS AN INDEPENDENT RISK FACTOR PREDICTING MORTALITY
Document Type and Number:
WIPO Patent Application WO2004106940
Kind Code:
A3
Abstract:
Disclosed are methods of characterising life expectancy of human individuals on the basis of measured relaxin levels. In one aspect of the invention the human individuals are end-stage-kidney-disease patients.

Inventors:
STASCH JOHANNES-PETER (DE)
GEHRMANN MATHIAS (DE)
HOCHER BERTHOLD (DE)
Application Number:
PCT/EP2004/005599
Publication Date:
April 07, 2005
Filing Date:
May 25, 2004
Export Citation:
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Assignee:
BAYER HEALTHCARE AG (DE)
STASCH JOHANNES-PETER (DE)
GEHRMANN MATHIAS (DE)
HOCHER BERTHOLD (DE)
International Classes:
G01N33/74; (IPC1-7): G01N33/74
Other References:
DSCHIETZIG THOMAS ET AL: "The pregnancy hormone relaxin is a player in human heart failure", FASEB JOURNAL, vol. 15, no. 12, October 2001 (2001-10-01), pages 2187 - 2195, XP002195177, ISSN: 0892-6638
YEUN J Y ET AL: "C-Reactive protein predicts all-cause and cardiovascular mortality in hemodialysis patients.", AMERICAN JOURNAL OF KIDNEY DISEASES: THE OFFICIAL JOURNAL OF THE NATIONAL KIDNEY FOUNDATION. UNITED STATES MAR 2000, vol. 35, no. 3, March 2000 (2000-03-01), pages 469 - 476, XP008024225, ISSN: 1523-6838
FERNANDEZ-REYES MARIA JOSE ET AL: "Inflammation and malnutrition as predictors of mortality in patients on hemodialysis", JN JOURNAL OF NEPHROLOGY, vol. 15, no. 2, March 2002 (2002-03-01), pages 136 - 143, XP002260579, ISSN: 1121-8428
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