Title:
SELECTIVE NON-STEROIDAL GLUCOCORTICOID RECEPTOR MODULATORS
Document Type and Number:
WIPO Patent Application WO2004075840
Kind Code:
A9
Abstract:
The present invention encompasses compounds of Formula (I) or pharmaceutically acceptable salts or hydrates thereof, which are useful as novel non-steroidal selective glucocorticoid receptor modulators for treating a variety of autoimmune and inflammatory diseases or conditions, and possess advantages over steroidal glucocorticoid ligands with respect to undesireable side-effects, efficacy, toxicity and/or metabolism. Pharmaceutical compositions and methods of use are also included.
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Inventors:
ALI AMJAD (US)
BERESIS RICHARD (US)
COLLETTI STEVEN L (US)
GRAHAM DONALD W (US)
TATA JAMES R (US)
THOMPSON CHRISTOPHER F (US)
BERESIS RICHARD (US)
COLLETTI STEVEN L (US)
GRAHAM DONALD W (US)
TATA JAMES R (US)
THOMPSON CHRISTOPHER F (US)
Application Number:
PCT/US2004/005199
Publication Date:
August 04, 2005
Filing Date:
February 20, 2004
Export Citation:
Assignee:
MERCK & CO INC (US)
ALI AMJAD (US)
BERESIS RICHARD (US)
COLLETTI STEVEN L (US)
GRAHAM DONALD W (US)
TATA JAMES R (US)
THOMPSON CHRISTOPHER F (US)
ALI AMJAD (US)
BERESIS RICHARD (US)
COLLETTI STEVEN L (US)
GRAHAM DONALD W (US)
TATA JAMES R (US)
THOMPSON CHRISTOPHER F (US)
International Classes:
A61K31/41; C07D231/54; C07D401/12; C07D403/12; C07D409/04; C07D409/12; A61K; (IPC1-7): A61K31/41
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