Title:
SESQUITERPENE POLYKETONE COMPOUND, PHARMACEUTICAL COMPOSITION AND USE
Document Type and Number:
WIPO Patent Application WO/2023/232125
Kind Code:
A1
Abstract:
The present invention relates to a sesquiterpene polyketone compound that can be used as immunomodulator, or a pharmaceutical composition. An activity experiment shows that the sesquiterpene polyketone compound provided by the present invention can be used as an immunomodulator for preventing and/or treating immune-related diseases.
Inventors:
GAO HAO (CN)
YIN ZHINAN (CN)
WANG CHUANXI (CN)
TANG XIN (CN)
YAO XINSHENG (CN)
YANG HENGWEN (CN)
HU DAN (CN)
LI ZHENHUA (CN)
KUANG RUNQIAO (CN)
REN FEIFEI (CN)
HAN XUE (CN)
YIN ZHINAN (CN)
WANG CHUANXI (CN)
TANG XIN (CN)
YAO XINSHENG (CN)
YANG HENGWEN (CN)
HU DAN (CN)
LI ZHENHUA (CN)
KUANG RUNQIAO (CN)
REN FEIFEI (CN)
HAN XUE (CN)
Application Number:
PCT/CN2023/097906
Publication Date:
December 07, 2023
Filing Date:
June 01, 2023
Export Citation:
Assignee:
UNIV JINAN (CN)
International Classes:
C07C47/57; A61P37/02; A61P37/06; A61P37/08; C07C47/575; C07C69/21; C07D209/46; C12P7/62; C12P17/10
Domestic Patent References:
| WO2016080796A2 | 2016-05-26 |
Foreign References:
| CN114956974A | 2022-08-30 | |||
| CN115040507A | 2022-09-13 | |||
| CN116444475A | 2023-07-18 |
Other References:
TANG XIN, WANG CHUANXI, WANG LEI, REN FEIFEI, KUANG RUNQIAO, LI ZHENHUA, HAN XUE, CHEN YIMING, CHEN GUODONG, WU XIUQING, LIU JIE, : "Aureane-type sesquiterpene tetraketides as a novel class of immunomodulators with interleukin-17A inhibitory activity", ACTA PHARMACEUTICA SINICA B, vol. 13, no. 9, 1 September 2023 (2023-09-01), pages 3930 - 3944, XP093115352, ISSN: 2211-3835, DOI: 10.1016/j.apsb.2023.03.017
邝润桥 (KUANG, RUNQIAO): "一株湿地来源漆斑属真菌次生代谢产物研究 (Non-official translation: Research on the Secondary Metabolites of a Fungus of the Genus Lactobacillus Originating from Wetland)", 暨南大学硕士学位论文 (MASTER'S DISSERTATION OF JINAN UNIVERSITY, 18 December 2018 (2018-12-18)
FAJARDO-HERNÁNDEZ CARLOS A., KHAN FIROZ SHAH TUGLAK, FLORES-BOCANEGRA LAURA, PRIETO-DAVÓ ALEJANDRA, WAN BAOJIE, MA RUI, QADER MALL: "Insights into the Chemical Diversity of Selected Fungi from the Tza Itzá Cenote of the Yucatan Peninsula", ACS OMEGA, ACS PUBLICATIONS, US, vol. 7, no. 14, 12 April 2022 (2022-04-12), US , pages 12171 - 12185, XP093116884, ISSN: 2470-1343, DOI: 10.1021/acsomega.2c00544
邝润桥 (KUANG, RUNQIAO): "一株湿地来源漆斑属真菌次生代谢产物研究 (Non-official translation: Research on the Secondary Metabolites of a Fungus of the Genus Lactobacillus Originating from Wetland)", 暨南大学硕士学位论文 (MASTER'S DISSERTATION OF JINAN UNIVERSITY, 18 December 2018 (2018-12-18)
FAJARDO-HERNÁNDEZ CARLOS A., KHAN FIROZ SHAH TUGLAK, FLORES-BOCANEGRA LAURA, PRIETO-DAVÓ ALEJANDRA, WAN BAOJIE, MA RUI, QADER MALL: "Insights into the Chemical Diversity of Selected Fungi from the Tza Itzá Cenote of the Yucatan Peninsula", ACS OMEGA, ACS PUBLICATIONS, US, vol. 7, no. 14, 12 April 2022 (2022-04-12), US , pages 12171 - 12185, XP093116884, ISSN: 2470-1343, DOI: 10.1021/acsomega.2c00544
Attorney, Agent or Firm:
BEIJING CEMO LEADER INTELLECTUAL PROPERTY AGENCY et al. (CN)
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